Gene Symbol | C1QA |
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Entrez Gene | 712 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent, A chain |
Other Description | complement C1q subcomponent subunit A|complement component 1, q subcomponent, alpha polypeptide|complement component C1q, A chain |
Swissprots | P02745 B2R4X2 Q5T963 |
Accessions | AAV40828 EAW95014 EAW95015 P02745 AF135157 AAD32626 AF260332 AAG44663 AK311980 BAG34919 BC030153 AAH30153 BC071986 AAH71986 BG548439 BX369252 EU832816 ACE87827 GQ129447 ACT64581 HQ447673 ADQ32158 NM_015991 NP_057075 |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection |
Human C1q full length protein - ab96363 from Abcam
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Human C1QA full length protein - ab157982 from Abcam
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Mouse C1q peptide - ab91203 from Abcam
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Recombinant Human C1q Protein - H00000712-P01 from Novus Biologicals
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C1QA-Antibody-C-term-Blocking-Peptide - BP7324b from Abgent, a WuXi AppTec company
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Complement C1q Protein (OPMA04352) - OPMA04352 from Aviva Systems Biology
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Human C1QA protein - orb244055 from Biorbyt
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C1QA Blocking Peptide - 33R-7113 from Fitzgerald
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C1q (native) - BA148 from Acris Antibodies
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C1q - P102-1 from Acris Antibodies
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C1q A subunit - H00000712-P01-10 from Acris Antibodies
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C1q A subunit - H00000712-P01-25 from Acris Antibodies
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C1QA fusion protein - Ag2141 from Proteintech Group
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Recombinant Human C1QA, GST-tagged - C1QA-10475H from Creative Biomart
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Recombinant Human Complement Component 1, q Subcomponent, A Chain - C1QA-4292H from Creative Biomart
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Native Human C1QA - C1QA-26126TH from Creative Biomart
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Recombinant Complement Component 1, Q Subcomponent A (C1qA) - RPD207Hu01 from Uscn Life Science Inc.
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Recombinant Complement Component 1, Q Subcomponent A (C1qA) - RPD207Mu01 from Uscn Life Science Inc.
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Recombinant Complement Component 1, Q Subcomponent A (C1qA) - RPD207Ra01 from Uscn Life Science Inc.
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Recombinant Human Complement C1q subcomponent subunit A(C1QA) - CSB-YP003637HU CSB-BP003637HU CSB-MP003637HU from Cusabio
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Recombinant human Complement C1q subcomponent subunit A - CSB-EP003637HU from Cusabio
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C1QA Protein - abx163670 from Abbexa
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C1q Protein - NBP1-87492PEP from Novus Biologicals
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C1QA-Blocking-Peptide-Center - BP20555c from Abgent, a WuXi AppTec company
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C1QA Peptide, Human - M34GP01916H from Creative Peptides
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