Gene Symbol | VWA5A |
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Entrez Gene | 4013 |
Alt Symbol | BCSC-1, BCSC1, LOH11CR2A |
Species | Human |
Gene Type | protein-coding |
Description | von Willebrand factor A domain containing 5A |
Other Description | breast cancer suppressor candidate 1|loss of heterozygosity 11 chromosomal region 2 gene A protein|loss of heterozygosity, 11, chromosomal region 2, gene A|ortholog of mouse AW551984|von Willebrand factor A domain-containing protein 5A |
Swissprots | Q9BVF8 Q6UN19 O00534 Q6UN20 |
Accessions | AAQ94867 AAQ94868 AAQ94869 EAW67570 EAW67571 EAW67572 EAW67573 O00534 AF002672 AAB60942 AK291698 BAF84387 AK295247 BAG58238 AK314934 BAG37440 AY366503 AAQ94871 AY366504 AAQ94872 AY366505 AAQ94873 AY366506 AAQ94874 AY366507 AAQ94875 AY366508 AAQ94876 BC001234 AAH01234 BM990294 BT006655 AAP35301 CB243896 XM_011542828 XP_011541130 NM_001130142 NP_001123614 NM_014622 NP_055437 NM_198315 NP_938057 |
Function | May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis. |
Tissue Specificity | Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested. {ECO:0000269|PubMed:14504409}. |
VWA5A CRISPR/Cas9 KO Plasmid (h) - sc-410870 from Santa Cruz Biotechnology
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VWA5A HDR Plasmid (h) - sc-410870-HDR from Santa Cruz Biotechnology
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VWA5A Double Nickase Plasmid (h) - sc-410870-NIC from Santa Cruz Biotechnology
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VWA5A Double Nickase Plasmid (h2) - sc-410870-NIC-2 from Santa Cruz Biotechnology
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VWA5A CRISPR Activation Plasmid (h) - sc-410870-ACT from Santa Cruz Biotechnology
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VWA5A CRISPR Activation Plasmid (h2) - sc-410870-ACT-2 from Santa Cruz Biotechnology
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VWA5A Lentiviral Activation Particles (h) - sc-410870-LAC from Santa Cruz Biotechnology
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VWA5A Lentiviral Activation Particles (h2) - sc-410870-LAC-2 from Santa Cruz Biotechnology
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VWA5A siRNA (h) - sc-96727 from Santa Cruz Biotechnology
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VWA5A shRNA Plasmid (h) - sc-96727-SH from Santa Cruz Biotechnology
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VWA5A shRNA (h) Lentiviral Particles - sc-96727-V from Santa Cruz Biotechnology
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Breast cancer suppressor candidate 1 RNAi - H00004013-R02 from Novus Biologicals
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Breast cancer suppressor candidate 1 RNAi - H00004013-R01 from Novus Biologicals
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MISSION® esiRNA - EHU157931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22764 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22764 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12414 from Sigma-Aldrich
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VWA5A siRNA (Human) - CRH2717 from Cohesion Biosciences
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VWA5A - MBS8205459 from MyBioSource
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shRNA set against Human VWA5A (NM_198315.2) - SHH445432 from Creative biogene
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shRNA set against Human LOH11CR2A(NM_014622.4) - SHH159005 from Creative biogene
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shRNA set against Human LOH11CR2A(NM_198315.2) - SHH159029 from Creative biogene
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shRNA set against Human LOH11CR2A(NM_014622.4) - SHH159047 from Creative biogene
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VWA5A shRNA Plasmid (Human) - CHH2717 from Cohesion Biosciences
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VWA5A miRNA 3'UTR clone - MiUTR1H-05867 from Creative biogene
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