Gene Symbol | ABHD12 |
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Entrez Gene | 26090 |
Alt Symbol | ABHD12A, BEM46L2, C20orf22, PHARC, dJ965G21.2 |
Species | Human |
Gene Type | protein-coding |
Description | abhydrolase domain containing 12 |
Other Description | 2-arachidonoylglycerol hydrolase|abhydrolase domain-containing protein 12|monoacylglycerol lipase ABHD12 |
Swissprots | Q5T710 B4DE71 Q5T711 A6NED4 Q8N2K0 Q96CR1 Q9BX05 Q9NPX7 A6NJ90 Q9UFV6 A8K450 |
Accessions | EAX10088 EAX10089 EAX10090 Q8N2K0 AK075023 BAC11357 AK290815 BAF83504 AK293495 BAG56982 AL117442 CAB55927 BC014049 AAH14049 BQ574269 BQ672998 BQ961739 HQ448169 ADQ32650 XM_005260698 XP_005260755 XM_005260699 XP_005260756 XM_005260700 XP_005260757 XM_011529214 XP_011527516 XM_011529215 XP_011527517 XM_011529216 XP_011527518 XM_011529217 XP_011527519 XM_011529218 XP_011527520 NM_001042472 NP_001035937 NM_015600 NP_056415 |
Function | Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways. {ECO:0000250|UniProtKB:Q99LR1, ECO:0000269|PubMed:22969151, ECO:0000269|PubMed:24027063}. |
Subcellular Location | Membrane {ECO:0000250|UniProtKB:Q99LR1}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q99LR1}. |
ABHD12 CRISPR/Cas9 KO Plasmid (h) - sc-405543 from Santa Cruz Biotechnology
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ABHD12 HDR Plasmid (h) - sc-405543-HDR from Santa Cruz Biotechnology
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ABHD12 Double Nickase Plasmid (h) - sc-405543-NIC from Santa Cruz Biotechnology
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ABHD12 Double Nickase Plasmid (h2) - sc-405543-NIC-2 from Santa Cruz Biotechnology
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ABHD12 CRISPR Activation Plasmid (h) - sc-405543-ACT from Santa Cruz Biotechnology
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ABHD12 CRISPR Activation Plasmid (h2) - sc-405543-ACT-2 from Santa Cruz Biotechnology
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ABHD12 Lentiviral Activation Particles (h) - sc-405543-LAC from Santa Cruz Biotechnology
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ABHD12 Lentiviral Activation Particles (h2) - sc-405543-LAC-2 from Santa Cruz Biotechnology
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ABHD12 siRNA (h) - sc-72416 from Santa Cruz Biotechnology
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ABHD12 shRNA Plasmid (h) - sc-72416-SH from Santa Cruz Biotechnology
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ABHD12 shRNA (h) Lentiviral Particles - sc-72416-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU090941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2654 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2654 from Sigma-Aldrich
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ABHD12 siRNA (Human) - CRH8702 from Cohesion Biosciences
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ABHD12 - MBS8241294 from MyBioSource
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shRNA set against Human ABHD12 (NM_015600.4) - SHH229410 from Creative biogene
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Human ABHD12 siRNA - orb269204 from Biorbyt
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ABHD12 shRNA Plasmid (Human) - CHH8702 from Cohesion Biosciences
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ABHD12 miRNA 3'UTR clone - MiUTR3H-12971 from Creative biogene
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ABHD12 miRNA 3'UTR clone - MiUTR3H-12972 from Creative biogene
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