Gene Symbol | PTPN12 |
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Entrez Gene | 5782 |
Alt Symbol | PTP-PEST, PTPG1 |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, non-receptor type 12 |
Other Description | protein-tyrosine phosphatase G1|tyrosine-protein phosphatase non-receptor type 12 |
Swissprots | B4DKY2 A4D1C5 Q05209 Q59FD6 E9PEH9 Q75MN8 Q16130 Q86XU4 E9PBR5 |
Accessions | AAQ96881 EAL24198 EAW77036 EAW77037 Q05209 AB209524 BAD92761 AK289573 BAF82262 AK296764 BAG59344 AK303602 BAG64617 AK314236 BC026004 BC050008 AAH50008 CN395133 D13380 BAA02648 M93425 AAA36529 S69182 AAB30045 S69183 AAB30046 S69184 AAB30047 XM_005250518 XP_005250575 XM_006716073 XP_006716136 XM_011516444 XP_011514746 NM_001131008 NP_001124480 NM_001131009 NP_001124481 NM_002835 NP_002826 |
Function | Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2. {ECO:0000269|PubMed:17329398}. |
Subcellular Location | Cytoplasm. Cell projection, podosome {ECO:0000250}. |
PTP-PEST CRISPR/Cas9 KO Plasmid (h) - sc-404863 from Santa Cruz Biotechnology
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PTP-PEST HDR Plasmid (h) - sc-404863-HDR from Santa Cruz Biotechnology
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PTP-PEST Double Nickase Plasmid (h) - sc-404863-NIC from Santa Cruz Biotechnology
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PTP-PEST Double Nickase Plasmid (h2) - sc-404863-NIC-2 from Santa Cruz Biotechnology
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PTP-PEST CRISPR Activation Plasmid (h) - sc-404863-ACT from Santa Cruz Biotechnology
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PTP-PEST CRISPR Activation Plasmid (h2) - sc-404863-ACT-2 from Santa Cruz Biotechnology
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PTP-PEST Lentiviral Activation Particles (h) - sc-404863-LAC from Santa Cruz Biotechnology
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PTP-PEST Lentiviral Activation Particles (h2) - sc-404863-LAC-2 from Santa Cruz Biotechnology
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PTP-PEST siRNA (h) - sc-39207 from Santa Cruz Biotechnology
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PTP-PEST shRNA Plasmid (h) - sc-39207-SH from Santa Cruz Biotechnology
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PTP-PEST shRNA (h) Lentiviral Particles - sc-39207-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006901 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0730 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0732 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2124 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2124 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06388 from Sigma-Aldrich
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PTPN12 siRNA (Human) - CRH3905 from Cohesion Biosciences
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PTPN12 RNAi - H00005782-R01 from Novus Biologicals
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shRNA set against Human PTPN12 (NM_002835.3) - SHH386444 from Creative biogene
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Human PTPN12 siRNA - orb264407 from Biorbyt
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PTPN12 shRNA Plasmid (Human) - CHH3905 from Cohesion Biosciences
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PTPN12 miRNA 3'UTR clone - MiUTR3H-03129 from Creative biogene
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PTPN12 miRNA 3'UTR clone - MiUTR3H-03130 from Creative biogene
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