Gene Symbol | MKLN1 |
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Entrez Gene | 4289 |
Alt Symbol | TWA2 |
Species | Human |
Gene Type | protein-coding |
Description | muskelin 1, intracellular mediator containing kelch motifs |
Other Description | muskelin |
Swissprots | A4D1M8 Q9NSK4 Q9UL63 Q9NUS8 A6NG43 |
Accessions | CAE89978 EAL24081 EAW83781 EAW83782 EAW83783 Q9UL63 AA284481 AA451916 AF047489 AAF06698 AF086386 AI928463 AK002024 BAA92042 AK025088 AK074367 AK294384 BAG57641 AK310452 AL162071 CAB82407 AL705061 AL833458 AW505004 BC002834 AAH02834 BC013938 BC067825 AAH67825 BE778355 BU945366 BX537433 CAD97675 BX538253 CB046426 DA172589 XM_005250356 XP_005250413 XM_006715993 XP_006716056 XM_011516224 XP_011514526 NM_001145354 NP_001138826 NM_013255 NP_037387 |
Function | Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1. {ECO:0000250|UniProtKB:O89050}. |
Subcellular Location | Cytoplasm {ECO:0000250|UniProtKB:O89050}. Cell projection, ruffle {ECO:0000250|UniProtKB:O89050}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:O89050}. Note=Colocalizes with actin fibers in the cell cortex. {ECO:0000250|UniProtKB:O89050}. |
Muskelin CRISPR/Cas9 KO Plasmid (h) - sc-409182 from Santa Cruz Biotechnology
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Muskelin HDR Plasmid (h) - sc-409182-HDR from Santa Cruz Biotechnology
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Muskelin Double Nickase Plasmid (h) - sc-409182-NIC from Santa Cruz Biotechnology
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Muskelin Double Nickase Plasmid (h2) - sc-409182-NIC-2 from Santa Cruz Biotechnology
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Muskelin CRISPR Activation Plasmid (h) - sc-409182-ACT from Santa Cruz Biotechnology
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Muskelin CRISPR Activation Plasmid (h2) - sc-409182-ACT-2 from Santa Cruz Biotechnology
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Muskelin Lentiviral Activation Particles (h) - sc-409182-LAC from Santa Cruz Biotechnology
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Muskelin Lentiviral Activation Particles (h2) - sc-409182-LAC-2 from Santa Cruz Biotechnology
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Muskelin siRNA (h) - sc-89673 from Santa Cruz Biotechnology
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Muskelin shRNA Plasmid (h) - sc-89673-SH from Santa Cruz Biotechnology
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Muskelin shRNA (h) Lentiviral Particles - sc-89673-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU062721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14380 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14380 from Sigma-Aldrich
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MKLN1 siRNA (Human) - CRH2908 from Cohesion Biosciences
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Mkln1 RNAi - H00004289-R01 from Novus Biologicals
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shRNA set against Human MKLN1 (NM_013255.4) - SHH342296 from Creative biogene
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Human MKLN1 siRNA - orb263410 from Biorbyt
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MKLN1 shRNA Plasmid (Human) - CHH2908 from Cohesion Biosciences
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