Gene Symbol |
Pla2g2a
|
Entrez Gene |
29692
|
Alt Symbol |
sPLA2
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
phospholipase A2, group IIA (platelets, synovial fluid)
|
Other Description |
GIIC sPLA2|eted enzyme type IIA phospholipase A2|group IIA phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2, membrane associated|platelet phospholipase A2
|
Swissprots |
P14423
|
Accessions |
AAA41223 CAA35909 EDL80890 EDL80891 P14423 AF365363 AAK52061 AY651027 AAT68713 CB772812 D00523 BAA00410 FQ220554 FQ227448 FQ234749 M25148 AAA41920 X74364 XM_006239146 XP_006239208 NM_031598 NP_113786
|
Function |
Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.
|
Subcellular Location |
Membrane; Peripheral membrane protein.
|
Top Pathways |
Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism
|