Gene Symbol | PPT2 |
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Entrez Gene | 9374 |
Alt Symbol | C6orf8, G14, PPT-2 |
Species | Human |
Gene Type | protein-coding |
Description | palmitoyl-protein thioesterase 2 |
Other Description | S-thioesterase G14|VE-statin2|lysosomal thioesterase PPT2|palmitoyl-protein hydrolase 2 |
Swissprots | Q5JQF0 G8JLE1 A8K9L4 Q5STJ6 Q99945 A2BFI2 Q5SSX6 Q9UMR5 Q5SSX4 A2ABC9 A2BFH7 A2BFH9 O14799 Q5JP14 A2ARM7 B0S868 Q5JP13 Q5STJ5 Q6FI80 Q5SSX5 Q5STJ4 A2ABD1 Q0P6K0 |
Accessions | AAB47495 EAX03591 EAX03592 EAX03593 EAX03594 EAX03595 EAX03596 Q9UMR5 AF020543 AAB80730 AI472281 AL110128 CAB53659 AM392834 CAL37712 BC000955 BC001355 AAH01355 CR533546 CAG38577 DA153675 DA352776 DA918701 EU832333 ACE87590 EU832418 ACE86903 Y17958 CAB46981 NM_001204103 NP_001191032 NM_005155 NP_005146 NM_138717 NP_619731 NM_138934 |
Function | Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S- thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins. {ECO:0000269|PubMed:10417332, ECO:0000269|PubMed:12855696, ECO:0000269|PubMed:9341199}. |
Subcellular Location | Lysosome {ECO:0000269|PubMed:9341199}. |
Tissue Specificity | Broadly expressed, with highest levels in skeletal muscle. {ECO:0000269|PubMed:9341199}. |
Top Pathways | Lysosome, Fatty acid elongation, Fatty acid metabolism |
PPT2 (D-14) - sc-169020 from Santa Cruz Biotechnology
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PPT2 (C-18) - sc-130238 from Santa Cruz Biotechnology
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PPT2 (FL-302) - sc-292953 from Santa Cruz Biotechnology
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Anti-PPT2 antibody - ab71470 from Abcam
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Anti-PPT2 antibody - ab123349 from Abcam
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Anti-PPT2 antibody - ab69882 from Abcam
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Anti-PPT2 Antibody (aa183-212, AP) - LS-C266992 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa183-212, Biotin) - LS-C266993 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa183-212, APC) - LS-C266994 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa183-212, FITC) - LS-C266995 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa183-212, Azide-free, HRP) - LS-C266996 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa183-212, PE) - LS-C266998 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa182-212) - LS-C324253 from LifeSpan Bioscience
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Anti-PPT2 Antibody (C-Terminus) - LS-C345702 from LifeSpan Bioscience
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Anti-PPT2 Antibody (aa183-212) - LS-C162102 from LifeSpan Bioscience
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PPT2 Antibody - H00009374-B01P from Novus Biologicals
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PPT2 Antibody - H00009374-A01 from Novus Biologicals
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PPT2 Antibody - H00009374-D01P from Novus Biologicals
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PPT2 Polyclonal Antibody - bs-11750R from Bioss
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Rabbit Anti-PPT2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11750R-A350 from Bioss
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Rabbit Anti-PPT2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11750R-A488 from Bioss
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Rabbit Anti-PPT2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11750R-A555 from Bioss
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Rabbit Anti-PPT2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11750R-A647 from Bioss
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Rabbit Anti-PPT2 Polyclonal Antibody, Cy3 Conjugated - bs-11750R-Cy3 from Bioss
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Rabbit Anti-PPT2 Polyclonal Antibody, Cy5 Conjugated - bs-11750R-Cy5 from Bioss
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