Gene Symbol | MREG |
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Entrez Gene | 55686 |
Alt Symbol | DSU, WDT2 |
Species | Human |
Gene Type | protein-coding |
Description | melanoregulin |
Other Description | dilute suppressor protein homolog|whn-dependent transcript 2 |
Swissprots | Q8N565 Q53R89 Q9P1S1 Q5XKB6 Q9NWC9 Q53TC1 |
Accessions | AAY14656 AAY14719 EAW70554 EAW70555 EAW70556 Q8N565 AF068290 AAF65179 AK000978 BAA91453 BC032747 AAH32747 BC082990 AAH82990 BQ928130 CA843296 CX781801 HQ448138 ADQ32619 XM_011511468 XP_011509770 XR_922965 XR_922966 NM_018000 NP_060470 |
Function | Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity). {ECO:0000250}. |
Subcellular Location | Apical cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Localizes to the inner segment and basal outer segment of rods in the retina. {ECO:0000250}. |
Tissue Specificity | Expressed in photoreceptor cells (at protein level). {ECO:0000269|PubMed:17260955}. |
MREG CRISPR/Cas9 KO Plasmid (h) - sc-405725 from Santa Cruz Biotechnology
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MREG HDR Plasmid (h) - sc-405725-HDR from Santa Cruz Biotechnology
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MREG Double Nickase Plasmid (h) - sc-405725-NIC from Santa Cruz Biotechnology
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MREG Double Nickase Plasmid (h2) - sc-405725-NIC-2 from Santa Cruz Biotechnology
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MREG CRISPR Activation Plasmid (h) - sc-405725-ACT from Santa Cruz Biotechnology
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MREG CRISPR Activation Plasmid (h2) - sc-405725-ACT-2 from Santa Cruz Biotechnology
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MREG Lentiviral Activation Particles (h) - sc-405725-LAC from Santa Cruz Biotechnology
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MREG Lentiviral Activation Particles (h2) - sc-405725-LAC-2 from Santa Cruz Biotechnology
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MREG siRNA (h) - sc-94777 from Santa Cruz Biotechnology
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MREG shRNA Plasmid (h) - sc-94777-SH from Santa Cruz Biotechnology
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MREG shRNA (h) Lentiviral Particles - sc-94777-V from Santa Cruz Biotechnology
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DSU RNAi - H00055686-R01 from Novus Biologicals
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MISSION® esiRNA - EHU021831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14529 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14529 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11321 from Sigma-Aldrich
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MREG siRNA (Human) - CRJ0832 from Cohesion Biosciences
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shRNA set against Human MREG (NM_018000.2) - SHH344232 from Creative biogene
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Human MREG siRNA - orb271333 from Biorbyt
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MREG shRNA Plasmid (Human) - CHJ0832 from Cohesion Biosciences
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MREG miRNA 3'UTR clone - MiUTR1H-06415 from Creative biogene
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