| Gene Symbol |
UBR3
|
| Entrez Gene |
130507
|
| Alt Symbol |
ZNF650
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin protein ligase E3 component n-recognin 3 (putative)
|
| Other Description |
E3 ubiquitin-protein ligase UBR3|N-recognin-3|ubiquitin-protein ligase E3-alpha-3|ubiquitin-protein ligase E3-alpha-III|zinc finger protein 650
|
| Swissprots |
Q6ZT12 B4DZR7 Q8IVE7 Q6ZR55 Q8ND96 Q6ZSC2 Q2KHN5
|
| Accessions |
AAY14890 EAX11248 EAX11249 EAX11250 Q6ZT12 AB095944 BAC23120 AI142128 AK094741 AK126998 BAC86783 AK127553 BAC87032 AK128490 BAC87462 AK303062 BAG64179 AL834144 CAD38857 BC044060 BC044594 BC113010 BF446017 BU158552 BU686724 BX281113 BX494687 BX649036 CR749469 CAH18299 DA108743 DA234864 DA301129 DA352029 DN831941 DR731153 XM_005246299 XP_005246356 XM_005246300 XP_005246357 XM_006712268 XP_006712331 XM_006712269 XP_006712332 XM_006712270 XP_006712333 XM_006712271 XP_006712334 XM_011510604 XP_011508906 XR_922841 XR_922842 NM_172070 NP_742067
|
| Function |
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|