Gene Symbol | MMP25 |
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Entrez Gene | 64386 |
Alt Symbol | MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 25 |
Other Description | leukolysin|matrix metallopeptidase-like 1|matrix metalloproteinase 20|matrix metalloproteinase 25|matrix metalloproteinase-25|matrix metalloproteinase-like 1|membrane-type 6 matrix metalloproteinase|membrane-type matrix metalloproteinase 6|membrane-type-6 matrix metalloproteinase |
Swissprots | D3DUA8 Q9NPA2 Q9H3Q0 |
Accessions | CAA05902 CCQ43687 EAW85413 EAW85415 Q9NPA2 AB042328 BAB20584 AF145442 AAF66697 AF185270 AAG17007 AJ003144 CAA05900 AJ239053 CAB94713 AJ272137 CAC03490 BC111412 BC167800 AAI67800 CB529891 XM_011522601 XP_011520903 XM_011522602 XP_011520904 XM_011522603 XP_011520905 XM_011522604 XP_011520906 XM_011522605 XP_011520907 XM_011522606 XP_011520908 NM_022468 NP_071913 NM_004142 NM_022718 |
Function | May activate progelatinase A. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas. |
MT-MMP-6 CRISPR/Cas9 KO Plasmid (h) - sc-406109 from Santa Cruz Biotechnology
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MT-MMP-6 HDR Plasmid (h) - sc-406109-HDR from Santa Cruz Biotechnology
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MT-MMP-6 Double Nickase Plasmid (h) - sc-406109-NIC from Santa Cruz Biotechnology
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MT-MMP-6 Double Nickase Plasmid (h2) - sc-406109-NIC-2 from Santa Cruz Biotechnology
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MT-MMP-6 CRISPR Activation Plasmid (h) - sc-406109-ACT from Santa Cruz Biotechnology
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MT-MMP-6 CRISPR Activation Plasmid (h2) - sc-406109-ACT-2 from Santa Cruz Biotechnology
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MT-MMP-6 Lentiviral Activation Particles (h) - sc-406109-LAC from Santa Cruz Biotechnology
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MT-MMP-6 Lentiviral Activation Particles (h2) - sc-406109-LAC-2 from Santa Cruz Biotechnology
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MT-MMP-6 siRNA (h) - sc-41573 from Santa Cruz Biotechnology
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MT-MMP-6 shRNA Plasmid (h) - sc-41573-SH from Santa Cruz Biotechnology
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MT-MMP-6 shRNA (h) Lentiviral Particles - sc-41573-V from Santa Cruz Biotechnology
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MMP-25/MT6-MMP RNAi - H00064386-R02 from Novus Biologicals
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MMP20 RNAi - H00009313-R01 from Novus Biologicals
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MMP-25/MT6-MMP RNAi - H00064386-R01 from Novus Biologicals
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MISSION® esiRNA - EHU140241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14434 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14434 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09904 from Sigma-Aldrich
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MMP25 siRNA (Human) - CRJ1998 from Cohesion Biosciences
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shRNA set against Human MMP25 (NM_022468.4) - SHH343056 from Creative biogene
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shRNA set against Human MMP25(NM_022468.4) - SHH193943 from Creative biogene
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Human MMP25 siRNA - orb272499 from Biorbyt
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MMP25 shRNA Plasmid (Human) - CHJ1998 from Cohesion Biosciences
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MMP25 miRNA 3'UTR clone - MiUTR1H-06356 from Creative biogene
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