Gene Symbol | PDLIM3 |
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Entrez Gene | 27295 |
Alt Symbol | ALP |
Species | Human |
Gene Type | protein-coding |
Description | PDZ and LIM domain 3 |
Other Description | PDZ and LIM domain protein 3|alpha-actinin-2-associated LIM protein|enigma homolog |
Swissprots | Q8N6Y6 B2R866 O60440 O43590 Q53GG5 Q9BVP4 O60439 |
Accessions | EAX04638 EAX04639 EAX04640 EAX04641 Q53GG5 AF002280 AAC16670 AF002282 AAC16672 AF039018 AAB96665 AK129607 BAC85195 AK129863 AK222966 BAD96686 AK313253 BAG36063 BC001017 BC027870 AAH27870 BI913867 BT007341 AAP36005 BX647263 C03422 CD625728 CR739525 DA898089 XM_011531874 XP_011530176 XR_938723 XR_938724 NM_001114107 NP_001107579 NM_001257962 NP_001244891 NM_001257963 NP_001244892 NM_014476 NP_055291 NR_047562 |
Function | May play a role in the organization of actin filament arrays within muscle cells. {ECO:0000250}. |
Subcellular Location | Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:10063829}. Note=Localizes to myofiber Z-lines. |
Tissue Specificity | Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific. {ECO:0000269|PubMed:9334352}. |
ALP CRISPR/Cas9 KO Plasmid (h) - sc-401877 from Santa Cruz Biotechnology
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ALP HDR Plasmid (h) - sc-401877-HDR from Santa Cruz Biotechnology
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ALP Double Nickase Plasmid (h) - sc-401877-NIC from Santa Cruz Biotechnology
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ALP Double Nickase Plasmid (h2) - sc-401877-NIC-2 from Santa Cruz Biotechnology
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ALP CRISPR Activation Plasmid (h) - sc-401877-ACT from Santa Cruz Biotechnology
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ALP CRISPR Activation Plasmid (h2) - sc-401877-ACT-2 from Santa Cruz Biotechnology
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ALP Lentiviral Activation Particles (h) - sc-401877-LAC from Santa Cruz Biotechnology
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ALP Lentiviral Activation Particles (h2) - sc-401877-LAC-2 from Santa Cruz Biotechnology
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ALP siRNA (h) - sc-72485 from Santa Cruz Biotechnology
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ALP shRNA Plasmid (h) - sc-72485-SH from Santa Cruz Biotechnology
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ALP shRNA (h) Lentiviral Particles - sc-72485-V from Santa Cruz Biotechnology
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PDLIM3 RNAi - H00027295-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN16571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16571 from Sigma-Aldrich
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PDLIM3 siRNA (Human) - CRH9062 from Cohesion Biosciences
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shRNA set against Human PDLIM3 (NM_014476.5) - SHH372936 from Creative biogene
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Human PDLIM3 siRNA - orb269564 from Biorbyt
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PDLIM3 shRNA Plasmid (Human) - CHH9062 from Cohesion Biosciences
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PDLIM3 miRNA 3'UTR clone - MiUTR3H-08020 from Creative biogene
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PDLIM3 miRNA 3'UTR clone - MiUTR3H-08021 from Creative biogene
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