Gene Symbol |
SLC19A1
|
Entrez Gene |
6573
|
Alt Symbol |
CHMD, FOLT, IFC1, REFC, RFC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 19 (folate transporter), member 1
|
Other Description |
IFC-1|RFC|folate transporter 1|intestinal folate carrier 1|placental folate transporter|reduced folate carrier protein|solute carrier family 19 member 1
|
Swissprots |
Q13026 P41440 B2R7U8 E9PFY4 O00553 B7Z8C3 O60227 Q9BTX8
|
Accessions |
AAC26162 AAC78834 CAB90483 EAX09331 EAX09332 EAX09333 EAX09334 EAX09335 EAX09336 EAX09337 P41440 AB209069 BAD92306 AF004354 AAB61417 AK303168 BAH13909 AK307623 AK310797 AK313125 BAG35945 BC003068 AAH03068 BC023005 BC128247 AAI28248 CB959876 CB995207 DC311922 DQ891831 ABM82757 DQ895016 ABM85942 S78996 AAB35058 U15939 AAA98442 U17566 AAA74914 U19720 AAC50180 XM_005261164 XP_005261221 XM_011529696 XP_011527998 XM_011529697 XP_011527999 XM_011529698 XP_011528000 XM_011529699 XP_011528001 XM_011529700 XP_011528002 XM_011529701 XP_011528003 XM_011529702 XP_011528004 XM_011529703 XP_011528005 XM_011529704 XP_011528006 XM_011529705 XP_011528007 XM_011529706 XP_011528008 XM_011529707 XP_011528009 XM_011529708 XP_011528010 XM_011529709 XP_011528011 XM_011529710 XP_011528012 NM_001205206 NP_001192135 NM_001205207 NP_001192136 NM_194255 NP_919231 NM_003056
|
Function |
Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Placenta, liver, and to a much smaller extent, in lung.
|
Top Pathways |
Vitamin digestion and absorption
|