| Gene Symbol |
PIGS
|
| Entrez Gene |
94005
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol glycan anchor biosynthesis, class S
|
| Other Description |
GPI transamidase component PIG-S|GPI transamidase subunit|phosphatidylinositol glycan, class S|phosphatidylinositol-glycan biosynthesis class S protein
|
| Swissprots |
Q96S52 Q6UVX6
|
| Accessions |
CAH05658 EAW51099 EAW51100 EAW51101 EAW51102 EAW51103 Q96S52 AB057723 BAB60853 AF161427 AAF28987 AK025825 AK055512 BAB70938 AK075428 BAC11615 AK127162 BAG54444 AK297046 BAG59572 AK314583 BAG37159 AW084841 AY359112 AAQ89470 BC001319 AAH01319 BC007301 AAH07301 BC069228 AAH69228 BX640839 CAE45912 DA591284 NM_033198 NP_149975
|
| Function |
Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. {ECO:0000269|PubMed:11483512}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Multi-pass membrane protein {ECO:0000269|PubMed:11483512}.
|
| Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|