| Gene Symbol | SDHB |
|---|---|
| Entrez Gene | 6390 |
| Alt Symbol | CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP |
| Species | Human |
| Gene Type | protein-coding |
| Description | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| Other Description | iron-sulfur subunit of complex II|succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
| Swissprots | Q9NQ12 B2R545 Q0QEY7 P21912 |
| Accessions | AAA80581 CAE47739 EAW94828 EAW94829 P21912 AK312056 BAG34992 BC007840 AAH07840 BF796275 BU554163 D10245 BAA01089 DQ403007 ABD77140 M32246 AAA35708 U17248 AAA81167 NM_003000 NP_002991 |
| Function | Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
| Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| Top Pathways | Citrate cycle (TCA cycle), Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |