Gene Symbol | SDHB |
---|---|
Entrez Gene | 6390 |
Alt Symbol | CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP |
Species | Human |
Gene Type | protein-coding |
Description | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
Other Description | iron-sulfur subunit of complex II|succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
Swissprots | Q9NQ12 B2R545 Q0QEY7 P21912 |
Accessions | AAA80581 CAE47739 EAW94828 EAW94829 P21912 AK312056 BAG34992 BC007840 AAH07840 BF796275 BU554163 D10245 BAA01089 DQ403007 ABD77140 M32246 AAA35708 U17248 AAA81167 NM_003000 NP_002991 |
Function | Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Citrate cycle (TCA cycle), Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
SDHB CRISPR/Cas9 KO Plasmid (h) - sc-401529 from Santa Cruz Biotechnology
|
||||||||
SDHB HDR Plasmid (h) - sc-401529-HDR from Santa Cruz Biotechnology
|
||||||||
SDHB Double Nickase Plasmid (h) - sc-401529-NIC from Santa Cruz Biotechnology
|
||||||||
SDHB Double Nickase Plasmid (h2) - sc-401529-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SDHB CRISPR Activation Plasmid (h) - sc-401529-ACT from Santa Cruz Biotechnology
|
||||||||
SDHB CRISPR Activation Plasmid (h2) - sc-401529-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SDHB Lentiviral Activation Particles (h) - sc-401529-LAC from Santa Cruz Biotechnology
|
||||||||
SDHB Lentiviral Activation Particles (h2) - sc-401529-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SDHB siRNA (h) - sc-44088 from Santa Cruz Biotechnology
|
||||||||
SDHB shRNA Plasmid (h) - sc-44088-SH from Santa Cruz Biotechnology
|
||||||||
SDHB shRNA (h) Lentiviral Particles - sc-44088-V from Santa Cruz Biotechnology
|
||||||||
SDHB RNAi - H00006390-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU144651 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19003 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19003 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR01163 from Sigma-Aldrich
|
||||||||
SDHB siRNA (Human) - CRH4315 from Cohesion Biosciences
|
||||||||
SDHB - MBS8220746 from MyBioSource
|
||||||||
shRNA set against Human SDHB (NM_003000.2) - SHH403416 from Creative biogene
|
||||||||
shRNA set against Human SDHB(NM_003000.2) - SHR192102 from Creative biogene
|
||||||||
Human SDHB siRNA - orb264817 from Biorbyt
|
||||||||
SDHB shRNA Plasmid (Human) - CHH4315 from Cohesion Biosciences
|
||||||||
SDHB miRNA 3'UTR clone - MiUTR1H-09216 from Creative biogene
|