Gene Symbol |
MTERF2
|
Entrez Gene |
80298
|
Alt Symbol |
MTERFD3, mTERFL
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mitochondrial transcription termination factor 2
|
Other Description |
MTERF domain containing 3|mTERF domain-containing protein 3, mitochondrial|mitochondrial transcription termination factor-like protein|transcription termination factor 2, mitochondrial
|
Swissprots |
Q9H7Y9 Q9H4L6 Q49AM1 Q53HM2
|
Accessions |
EAW97792 EAW97793 EAW97794 Q49AM1 AK024124 BAB14834 AK222558 BAD96278 AL832827 CAI46173 AY008301 AAG22860 BC008486 BC025984 AAH25984 BC036066 AAH36066 BC050361 BC068468 DA074327 EU446603 ABZ92132 XM_006719613 XP_006719676 XM_011538767 XP_011537069 NM_001033050 NP_001028222 NM_025198 NP_079474
|
Function |
Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:16226716}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}.
|
Tissue Specificity |
Expressed in skeletal muscle, heart, liver and pancreas. {ECO:0000269|PubMed:16226716}.
|