| Gene Symbol |
HPRT1
|
| Entrez Gene |
101867079
|
| Alt Symbol |
HGPRT, HGPRTase, HPRT, QflA-10339
|
| Species |
Monkey
|
| Gene Type |
protein-coding
|
| Description |
Hypoxanthine-guanine phosphoribosyltransferase
|
| Other Description |
hypoxanthine-guanine phosphoribosyltransferase
|
| Swissprots |
Q4R5K4 Q6LDD9
|
| Accessions |
Q6LDD9 AB169539 BAE01621 XM_005594619 XP_005594676 XM_005594620 XP_005594677 NM_001283594 NP_001270523
|
| Function |
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Top Pathways |
Purine metabolism, Drug metabolism - other enzymes
|