| Gene Symbol | ALDH1B1 |
|---|---|
| Entrez Gene | 219 |
| Alt Symbol | ALDH5, ALDHX |
| Species | Human |
| Gene Type | protein-coding |
| Description | aldehyde dehydrogenase 1 family, member B1 |
| Other Description | ALDH class 2|acetaldehyde dehydrogenase 5|aldehyde dehydrogenase 5|aldehyde dehydrogenase X, mitochondrial |
| Swissprots | P30837 B2R8F0 Q8WX76 Q9BV45 |
| Accessions | AAA96830 EAW58252 P30837 AI803741 AK225950 AK297020 BAG59552 AK313344 BAG36147 BC001619 AAH01619 BE889810 BT007418 AAP36086 DA599259 DB256700 DQ890749 ABM81675 EU176489 ABW03290 XM_011517802 XP_011516104 NM_000692 NP_000683 |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. |
| Subcellular Location | Mitochondrion matrix. |
| Tissue Specificity | Liver, testis and to a lesser extent in brain. |
| Top Pathways | Glycolysis / Gluconeogenesis, Tryptophan metabolism, Fatty acid degradation, Pyruvate metabolism, Glycerolipid metabolism |