Gene Symbol | ALDH1B1 |
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Entrez Gene | 219 |
Alt Symbol | ALDH5, ALDHX |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 1 family, member B1 |
Other Description | ALDH class 2|acetaldehyde dehydrogenase 5|aldehyde dehydrogenase 5|aldehyde dehydrogenase X, mitochondrial |
Swissprots | P30837 B2R8F0 Q8WX76 Q9BV45 |
Accessions | AAA96830 EAW58252 P30837 AI803741 AK225950 AK297020 BAG59552 AK313344 BAG36147 BC001619 AAH01619 BE889810 BT007418 AAP36086 DA599259 DB256700 DQ890749 ABM81675 EU176489 ABW03290 XM_011517802 XP_011516104 NM_000692 NP_000683 |
Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Liver, testis and to a lesser extent in brain. |
Top Pathways | Glycolysis / Gluconeogenesis, Tryptophan metabolism, Fatty acid degradation, Pyruvate metabolism, Glycerolipid metabolism |
ALDH1B1 CRISPR/Cas9 KO Plasmid (h) - sc-404562 from Santa Cruz Biotechnology
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ALDH1B1 HDR Plasmid (h) - sc-404562-HDR from Santa Cruz Biotechnology
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ALDH1B1 Double Nickase Plasmid (h) - sc-404562-NIC from Santa Cruz Biotechnology
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ALDH1B1 Double Nickase Plasmid (h2) - sc-404562-NIC-2 from Santa Cruz Biotechnology
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ALDH1B1 CRISPR Activation Plasmid (h) - sc-404562-ACT from Santa Cruz Biotechnology
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ALDH1B1 CRISPR Activation Plasmid (h2) - sc-404562-ACT-2 from Santa Cruz Biotechnology
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ALDH1B1 Lentiviral Activation Particles (h) - sc-404562-LAC from Santa Cruz Biotechnology
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ALDH1B1 Lentiviral Activation Particles (h2) - sc-404562-LAC-2 from Santa Cruz Biotechnology
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ALDH1B1 siRNA (h) - sc-92848 from Santa Cruz Biotechnology
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ALDH1B1 shRNA Plasmid (h) - sc-92848-SH from Santa Cruz Biotechnology
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ALDH1B1 shRNA (h) Lentiviral Particles - sc-92848-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1782 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1782 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09720 from Sigma-Aldrich
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ALDH1B1 siRNA (Human) - CRH0154 from Cohesion Biosciences
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ALDH1B1 - MBS8220457 from MyBioSource
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shRNA set against Human ALDH1B1 (NM_000692.4) - SHH234834 from Creative biogene
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ALDH1B1 shRNA Plasmid (Human) - CHH0154 from Cohesion Biosciences
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ALDH1B1 miRNA 3'UTR clone - MiUTR3H-00006 from Creative biogene
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