| Gene Symbol |
SLC25A19
|
| Entrez Gene |
60386
|
| Alt Symbol |
DNC, MCPHA, MUP1, THMD3, THMD4, TPC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
|
| Other Description |
microcephaly, Amish|mitochondrial thiamine pyrophosphate carrier|mitochondrial uncoupling protein 1|solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19
|
| Swissprots |
E9PF74 Q9HC21 Q6V9R7
|
| Accessions |
CAC37793 CAF86907 EAW89267 EAW89268 EAW89269 Q9HC21 AA743427 AF182404 AAG16903 AJ251857 CAC27560 AK075239 BAC11492 AK097882 BAG53545 AK225881 AL833387 CAI46136 AY346372 AAQ54327 BC001075 AAH01075 BC005120 AAH05120 BM455504 BU177306 BU607955 DA605220 DB482052 DQ892760 ABM83686 DQ896005 ABM86983 XM_005257559 XP_005257616 XM_005257560 XP_005257617 XM_005257561 XP_005257618 XM_005257562 XP_005257619 XM_006722007 XP_006722070 XM_011525098 XP_011523400 NM_001126121 NP_001119593 NM_001126122 NP_001119594 NM_021734 NP_068380
|
| Function |
Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. {ECO:0000269|PubMed:18280798}.
|
| Subcellular Location |
Mitochondrion inner membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in all tissues examined except for placenta. Highest levels in colon, kidney, lung, testis, spleen, and brain. {ECO:0000269|PubMed:11226231}.
|