Gene Symbol | PHKA2 |
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Entrez Gene | 5256 |
Alt Symbol | GSD9A, PHK, PYK, PYKL, XLG, XLG2 |
Species | Human |
Gene Type | protein-coding |
Description | phosphorylase kinase, alpha 2 (liver) |
Other Description | phosphorylase b kinase regulatory subunit alpha liver isoform|phosphorylase b kinase regulatory subunit alpha, liver isoform|phosphorylase kinase alpha L subunit|phosphorylase kinase alpha-subunit |
Swissprots | Q9UDA1 Q7Z6W0 Q96CR3 Q6LAJ5 A8K1T1 P46019 |
Accessions | AAD32846 CAA75420 CAA75421 EAW98951 P46019 AK056812 AK092480 AK289996 BAF82685 AY429559 AY429560 AY429561 AY429562 AY429563 BC014036 AAH14036 BC114375 CD722555 D38616 BAA07606 DB458123 DQ893677 ABM84603 DQ895560 ABM86486 W63591 X73875 CAA52084 X80497 CAA56662 XM_005274548 XP_005274605 XM_005274550 XP_005274607 XM_006724496 XP_006724559 XM_006724498 XP_006724561 XM_011545537 XP_011543839 XM_011545538 XP_011543840 XR_950461 NM_000292 NP_000283 |
Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Predominantly expressed in liver and other non-muscle tissues. |
Top Pathways | Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway |
PHKA2 CRISPR/Cas9 KO Plasmid (h) - sc-408762 from Santa Cruz Biotechnology
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PHKA2 HDR Plasmid (h) - sc-408762-HDR from Santa Cruz Biotechnology
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PHKA2 Double Nickase Plasmid (h) - sc-408762-NIC from Santa Cruz Biotechnology
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PHKA2 Double Nickase Plasmid (h2) - sc-408762-NIC-2 from Santa Cruz Biotechnology
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PHKA2 CRISPR Activation Plasmid (h) - sc-408762-ACT from Santa Cruz Biotechnology
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PHKA2 CRISPR Activation Plasmid (h2) - sc-408762-ACT-2 from Santa Cruz Biotechnology
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PHKA2 Lentiviral Activation Particles (h) - sc-408762-LAC from Santa Cruz Biotechnology
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PHKA2 Lentiviral Activation Particles (h2) - sc-408762-LAC-2 from Santa Cruz Biotechnology
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PHKA2 siRNA (h) - sc-76121 from Santa Cruz Biotechnology
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PHKA2 shRNA Plasmid (h) - sc-76121-SH from Santa Cruz Biotechnology
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PHKA2 shRNA (h) Lentiviral Particles - sc-76121-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU030971 from Sigma-Aldrich
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MISSION® siRNA - SIHK1615 from Sigma-Aldrich
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MISSION® siRNA - SIHK1614 from Sigma-Aldrich
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MISSION® siRNA - SIHK1613 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1674 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1674 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05898 from Sigma-Aldrich
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PHKA2 siRNA (Human) - CRH3509 from Cohesion Biosciences
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PHKA2 RNAi - H00005256-R02 from Novus Biologicals
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shRNA set against Human PHKA2 (NM_000292.2) - SHH374880 from Creative biogene
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PHKA2 shRNA Plasmid (Human) - CHH3509 from Cohesion Biosciences
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PHKA2 miRNA 3'UTR clone - MiUTR3H-02940 from Creative biogene
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