Gene Symbol | Agxt |
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Entrez Gene | 11611 |
Alt Symbol | AGT, Agt1, Agxt1, SPT |
Species | Mouse |
Gene Type | protein-coding |
Description | alanine-glyoxylate aminotransferase |
Other Description | alanine--glyoxylate aminotransferase|alanine-glyoxylate aminotransferase 1|serine--pyruvate aminotransferase, mitochondrial|serine--pyruvate aminotransferase, peroxisomal|serine-pyruvate aminotransferase |
Swissprots | O35423 Q8R128 |
Accessions | EDL39971 EDL39972 O35423 AF027730 AAB82001 AK149432 BAE28872 BB868742 BC025799 AAH25799 NM_001276710 NP_001263639 NM_016702 NP_057911 |
Function | Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. Peroxisome {ECO:0000250}. |
Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Glyoxylate and dicarboxylate metabolism, Alanine, aspartate and glutamate metabolism, Carbon metabolism |
AGXT CRISPR/Cas9 KO Plasmid (m) - sc-419052 from Santa Cruz Biotechnology
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AGXT HDR Plasmid (m) - sc-419052-HDR from Santa Cruz Biotechnology
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AGXT Double Nickase Plasmid (m) - sc-419052-NIC from Santa Cruz Biotechnology
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AGXT Double Nickase Plasmid (m2) - sc-419052-NIC-2 from Santa Cruz Biotechnology
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AGXT CRISPR Activation Plasmid (m) - sc-419052-ACT from Santa Cruz Biotechnology
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AGXT CRISPR Activation Plasmid (m2) - sc-419052-ACT-2 from Santa Cruz Biotechnology
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AGXT Lentiviral Activation Particles (m) - sc-419052-LAC from Santa Cruz Biotechnology
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AGXT Lentiviral Activation Particles (m2) - sc-419052-LAC-2 from Santa Cruz Biotechnology
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AGXT siRNA (m) - sc-140910 from Santa Cruz Biotechnology
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AGXT shRNA Plasmid (m) - sc-140910-SH from Santa Cruz Biotechnology
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AGXT shRNA (m) Lentiviral Particles - sc-140910-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN26425 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26425 from Sigma-Aldrich
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AGXT siRNA (Mouse) - CRM0111 from Cohesion Biosciences
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AGXT - MBS827006 from MyBioSource
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shRNA set against Mouse AGXT (NM_016702.2) - SHH233558 from Creative biogene
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shRNA set against Mouse Agxt(NM_016702.2) - SHG046661 from Creative biogene
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AGXT CRISPR/Cas9 KO Plasmid (m2) - sc-419052-KO-2 from Santa Cruz Biotechnology
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AGXT HDR Plasmid (m2) - sc-419052-HDR-2 from Santa Cruz Biotechnology
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Mouse AGXT siRNA - orb279587 from Biorbyt
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AGXT shRNA Plasmid (Mouse) - CHM0111 from Cohesion Biosciences
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AGXT miRNA 3'UTR clone - MiUTR1M-01305 from Creative biogene
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