| Gene Symbol |
LIMS1
|
| Entrez Gene |
3987
|
| Alt Symbol |
PINCH, PINCH-1, PINCH1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
LIM and senescent cell antigen-like domains 1
|
| Other Description |
LIM and senescent cell antigen-like-containing domain protein 1|particularly interesting new Cys-His protein 1|renal carcinoma antigen NY-REN-48
|
| Swissprots |
Q9BS44 B2RAJ4 B7Z7R3 P48059 Q53TE0 B7Z907 B7Z483
|
| Accessions |
AAY14983 CBX53845 EAW53877 EAW53878 EAW53879 EAW53880 P48059 AF527759 AF527760 AF527761 AF527762 AF527763 AK025661 AK098109 AK296992 BAH12469 AK302411 BAH13699 AK304260 BAH14143 AK310547 AK314217 BAG36891 AL110164 BC005341 AAH05341 BC015843 BC022365 BG942518 DC401794 EU446859 ABZ92388 U09284 AAA20086 XM_005263946 XP_005264003 XM_005263948 XP_005264005 XM_005263949 XP_005264006 XM_005263950 XP_005264007 XM_005263951 XP_005264008 NM_001193482 NP_001180411 NM_001193483 NP_001180412 NM_001193484 NP_001180413 NM_001193485 NP_001180414 NM_001193488 NP_001180417 NM_004987 NP_004978
|
| Function |
Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.
|
| Subcellular Location |
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
|
| Tissue Specificity |
Expressed in most tissues except in the brain.
|