| Gene Symbol |
Atp1a1
|
| Entrez Gene |
24211
|
| Alt Symbol |
Nkaa1b
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
ATPase, Na+/K+ transporting, alpha 1 polypeptide
|
| Other Description |
ATPase, Na+K+ transporting, alpha 1|Na(+)/K(+) ATPase alpha-1 subunit|sodium pump subunit alpha-1|sodium/potassium-transporting ATPase subunit alpha-1
|
| Swissprots |
Q64609 P06685
|
| Accessions |
CAA37325 CAA37326 EDL85522 EDL85523 P06685 BC061968 AAH61968 FQ213537 FQ220647 FQ229594 M11733 AAA40783 M14511 AAA40775 M28647 AAA41671 M74494 AAA41670 X05882 CAA29306 NM_012504 NP_036636
|
| Function |
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Melanosome {ECO:0000250}.
|
| Top Pathways |
Salivary secretion, Cardiac muscle contraction, Aldosterone-regulated sodium reabsorption, cAMP signaling pathway, Thyroid hormone synthesis
|