| Gene Symbol | TRA2B |
|---|---|
| Entrez Gene | 615156 |
| Alt Symbol | SFRS10 |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | transformer 2 beta homolog (Drosophila) |
| Other Description | TRA-2 beta|TRA2-beta|splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)|transformer-2 protein homolog B|transformer-2 protein homolog beta |
| Swissprots | Q3ZBT6 |
| Accessions | DAA33375 Q3ZBT6 BC103113 AAI03114 XM_010801244 XP_010799546 XM_010801245 XP_010799547 NM_001034776 NP_001029948 |
| Function | Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000250}. |
| Top Pathways | Spliceosome |