| Gene Symbol |
TRA2B
|
| Entrez Gene |
615156
|
| Alt Symbol |
SFRS10
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
transformer 2 beta homolog (Drosophila)
|
| Other Description |
TRA-2 beta|TRA2-beta|splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)|transformer-2 protein homolog B|transformer-2 protein homolog beta
|
| Swissprots |
Q3ZBT6
|
| Accessions |
DAA33375 Q3ZBT6 BC103113 AAI03114 XM_010801244 XP_010799546 XM_010801245 XP_010799547 NM_001034776 NP_001029948
|
| Function |
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Top Pathways |
Spliceosome
|