Gene Symbol | Ddah1 |
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Entrez Gene | 64157 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | dimethylarginine dimethylaminohydrolase 1 |
Other Description | DDAH-1|DDAHI|N(G),N(G)-dimethylarginine dimethylaminohydrolase 1|NG,NG dimethylarginine dimethylaminohydrolase|dimethylargininase-1 |
Swissprots | O08557 |
Accessions | EDL82408 EDL82409 O08557 FQ220049 NM_022297 NP_071633 |
Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. {ECO:0000269|PubMed:16632550}. |
Tissue Specificity | Detected in red blood cells (at protein level). Widely distributed, high amounts found in kidney, brain, aorta and pancreas. {ECO:0000269|PubMed:16632550}. |
CompoZr® Knockout ZFN Kit - CKOZFN52822 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND52822 from Sigma-Aldrich
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DDAH1 siRNA (Rat) - CRR1817 from Cohesion Biosciences
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DDAH1 - MBS8221112 from MyBioSource
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shRNA set against Rat Ddah1(NM_022297.2) - SHG225413 from Creative biogene
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Rat DDAH1 siRNA - orb296666 from Biorbyt
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DDAH1 shRNA Plasmid (Rat) - CHR1817 from Cohesion Biosciences
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DDAH1 miRNA 3'UTR clone - MiUTR1R-01401 from Creative biogene
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