| Gene Symbol | AGTR2 |
|---|---|
| Entrez Gene | 186 |
| Alt Symbol | AT2, ATGR2, MRX88 |
| Species | Human |
| Gene Type | protein-coding |
| Description | angiotensin II receptor, type 2 |
| Other Description | angiotensin II type-2 receptor|type-2 angiotensin II receptor |
| Swissprots | Q6FGY7 Q13016 B2R9V1 P50052 |
| Accessions | AAA50762 AAA61794 AAA84900 AAA85851 AAA98990 AAB34100 AAP72969 AAP84355 AAS45437 EAW51502 P50052 AI911273 AK313927 BAG36648 BC095504 AAH95504 CR541969 CAG46767 CR738498 DA538369 U16957 AAA67753 X87723 CAA61022 XM_011537533 XP_011535835 NM_000686 NP_000677 |
| Function | Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. {ECO:0000269|PubMed:15123706}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine. {ECO:0000269|PubMed:12089445}. |
| Top Pathways | Adrenergic signaling in cardiomyocytes, Renin-angiotensin system, Neuroactive ligand-receptor interaction |