Gene Symbol |
Pitrm1
|
Entrez Gene |
69617
|
Alt Symbol |
2310012C15Rik, AA410010, MP-1, MP1, Ntup1, PreP, mKIAA1104
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
pitrilysin metallepetidase 1
|
Other Description |
nuclear transplantation upregulated protein 1|pitrilysin metalloprotease 1|pitrilysin metalloproteinase 1|presequence protease, mitochondrial
|
Swissprots |
Q4KUG2 Q922N1 Q4KUG3 Q3URQ8 Q6ZPX6 Q3TPP0 Q3THC4 Q8K411 Q9CV63 Q3TJI1
|
Accessions |
EDL32268 Q8K411 AF513714 AAM49783 AK009313 BAB26211 AK129292 BAC98102 AK141277 BAE24630 AK147837 BAE28172 AK164235 BAE37695 AK167426 BAE39514 AK168335 BAE40273 AK183554 AK185733 AK193186 AK194889 AK195287 AK203962 AK215334 AK216728 AK219858 AY779273 AAX11355 AY779274 AAX11356 BC006917 AAH06917 XM_006516508 XP_006516571 XM_006516509 XP_006516572 XR_382015 NM_145131 NP_660113
|
Function |
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion matrix {ECO:0000250}.
|