Gene Symbol | ADRA2C |
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Entrez Gene | 152 |
Alt Symbol | ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR |
Species | Human |
Gene Type | protein-coding |
Description | adrenoceptor alpha 2C |
Other Description | adrenergic, alpha-2C-, receptor|alpha-2 adrenergic receptor subtype C4|alpha-2C adrenergic receptor|alpha-2C adrenoceptor|alpha-2C adrenoreceptor|alpha-2C-adrenergic receptor|alpha-2CAR|alpha2-AR-C4 |
Swissprots | P18825 Q9HB49 P35369 |
Accessions | AAC78723 AAG28076 AAG28077 AAR18071 AAT02221 AAY41059 ABY87522 BAA02737 CAN37604 CBX55893 P18825 BC142625 AAI42626 J03853 AAA35513 NM_000683 NP_000674 |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction |
α 2C -AR CRISPR/Cas9 KO Plasmid (h) - sc-404948 from Santa Cruz Biotechnology
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α 2C -AR HDR Plasmid (h) - sc-404948-HDR from Santa Cruz Biotechnology
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α 2C -AR Double Nickase Plasmid (h) - sc-404948-NIC from Santa Cruz Biotechnology
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α 2C -AR Double Nickase Plasmid (h2) - sc-404948-NIC-2 from Santa Cruz Biotechnology
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α 2C -AR CRISPR Activation Plasmid (h) - sc-404948-ACT from Santa Cruz Biotechnology
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α 2C -AR CRISPR Activation Plasmid (h2) - sc-404948-ACT-2 from Santa Cruz Biotechnology
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α 2C -AR Lentiviral Activation Particles (h) - sc-404948-LAC from Santa Cruz Biotechnology
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α 2C -AR Lentiviral Activation Particles (h2) - sc-404948-LAC-2 from Santa Cruz Biotechnology
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α 2C -AR siRNA (h) - sc-29622 from Santa Cruz Biotechnology
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α 2C -AR shRNA Plasmid (h) - sc-29622-SH from Santa Cruz Biotechnology
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α 2C -AR shRNA (h) Lentiviral Particles - sc-29622-V from Santa Cruz Biotechnology
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alpha-2C Adrenergic R/ADRA2C RNAi - H00000152-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2902 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2902 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04703 from Sigma-Aldrich
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ADRA2C siRNA (Human) - CRH0106 from Cohesion Biosciences
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ADRA2C - MBS8202270 from MyBioSource
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shRNA set against Human ADRA2C (NM_000683.3) - SHH232730 from Creative biogene
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shRNA set against Human ADRA2C(NM_000683.3) - SHG044461 from Creative biogene
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ADRA2C shRNA Plasmid (Human) - CHH0106 from Cohesion Biosciences
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ADRA2C miRNA 3'UTR clone - MiUTR1H-00218 from Creative biogene
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