Gene Symbol | ADAM7 |
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Entrez Gene | 8756 |
Alt Symbol | ADAM 7, ADAM-7, EAPI, GP-83, GP83 |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase domain 7 |
Other Description | a disintegrin and metalloproteinase domain 7|disintegrin and metalloproteinase domain-containing protein 7|epididymal apical protein I|sperm maturation-related glycoprotein GP-83 |
Swissprots | A8K8X7 Q6PEJ6 O75959 Q9H2U9 |
Accessions | EAW63606 Q9H2U9 AF090327 AAC36742 AF215824 AAG43987 AK292492 BAF85181 BC043207 AAH43207 BC058037 AAH58037 BC141422 AAI41423 BC148735 AAI48736 DB077360 XM_005273668 XP_005273725 XM_005273669 XP_005273726 XM_005273670 XP_005273727 XM_005273671 XP_005273728 XM_005273672 XP_005273729 XM_005273673 XP_005273730 NM_003817 NP_003808 |
Function | May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Not detected in healthy melanocytes. Expressed in melanoma cells. {ECO:0000269|PubMed:21618342}. |
ADAM7 CRISPR/Cas9 KO Plasmid (h) - sc-409479 from Santa Cruz Biotechnology
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ADAM7 HDR Plasmid (h) - sc-409479-HDR from Santa Cruz Biotechnology
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ADAM7 Double Nickase Plasmid (h) - sc-409479-NIC from Santa Cruz Biotechnology
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ADAM7 Double Nickase Plasmid (h2) - sc-409479-NIC-2 from Santa Cruz Biotechnology
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ADAM7 CRISPR Activation Plasmid (h) - sc-409479-ACT from Santa Cruz Biotechnology
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ADAM7 CRISPR Activation Plasmid (h2) - sc-409479-ACT-2 from Santa Cruz Biotechnology
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ADAM7 Lentiviral Activation Particles (h) - sc-409479-LAC from Santa Cruz Biotechnology
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ADAM7 Lentiviral Activation Particles (h2) - sc-409479-LAC-2 from Santa Cruz Biotechnology
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ADAM7 siRNA (h) - sc-41404 from Santa Cruz Biotechnology
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ADAM7 shRNA Plasmid (h) - sc-41404-SH from Santa Cruz Biotechnology
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ADAM7 shRNA (h) Lentiviral Particles - sc-41404-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU092231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2822 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2822 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01571 from Sigma-Aldrich
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ADAM7 siRNA (Human) - CRH5769 from Cohesion Biosciences
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ADAM7 - MBS8224084 from MyBioSource
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shRNA set against Human ADAM7 (NM_003817.3) - SHH231678 from Creative biogene
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ADAM7 shRNA Plasmid (Human) - CHH5769 from Cohesion Biosciences
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ADAM7 miRNA 3'UTR clone - MiUTR4H-TG00137 from Creative biogene
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