Gene Symbol | PLOD3 |
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Entrez Gene | 8985 |
Alt Symbol | LH3 |
Species | Human |
Gene Type | protein-coding |
Description | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 |
Other Description | lysine hydroxylase 3|lysyl hydroxlase 3|lysyl hydroxylase 3|procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 |
Swissprots | Q540C3 O60568 B2R6W6 |
Accessions | AAD45831 AAF63701 CDM55391 CDM55572 EAW50205 O60568 AF046889 AAC39753 AF068229 AAC34808 AK075338 BAG52115 AK297559 BAG59952 AK298537 BAG60737 AK312743 BAG35613 AL049952 CAB43221 AY220458 AAO61775 BC011674 AAH11674 BC018946 BF941815 NM_001084 NP_001075 |
Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
Subcellular Location | Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. |
Top Pathways | Other types of O-glycan biosynthesis, Lysine degradation |
LLH3 CRISPR/Cas9 KO Plasmid (h) - sc-407050 from Santa Cruz Biotechnology
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LLH3 HDR Plasmid (h) - sc-407050-HDR from Santa Cruz Biotechnology
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LLH3 Double Nickase Plasmid (h) - sc-407050-NIC from Santa Cruz Biotechnology
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LLH3 Double Nickase Plasmid (h2) - sc-407050-NIC-2 from Santa Cruz Biotechnology
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LLH3 CRISPR Activation Plasmid (h) - sc-407050-ACT from Santa Cruz Biotechnology
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LLH3 CRISPR Activation Plasmid (h2) - sc-407050-ACT-2 from Santa Cruz Biotechnology
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LLH3 Lentiviral Activation Particles (h) - sc-407050-LAC from Santa Cruz Biotechnology
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LLH3 Lentiviral Activation Particles (h2) - sc-407050-LAC-2 from Santa Cruz Biotechnology
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LLH3 siRNA (h) - sc-60952 from Santa Cruz Biotechnology
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LLH3 shRNA Plasmid (h) - sc-60952-SH from Santa Cruz Biotechnology
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LLH3 shRNA (h) Lentiviral Particles - sc-60952-V from Santa Cruz Biotechnology
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PLOD3 RNAi - H00008985-R01 from Novus Biologicals
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MISSION® esiRNA - EHU023201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16995 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16995 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01903 from Sigma-Aldrich
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PLOD3 siRNA (Human) - CRH5927 from Cohesion Biosciences
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shRNA set against Human PLOD3(NM_001084.4) - SHR123366 from Creative biogene
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PLOD3 shRNA Plasmid (Human) - CHH5927 from Cohesion Biosciences
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PLOD3 miRNA 3'UTR clone - MiUTR1H-08013 from Creative biogene
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