Gene Symbol | WNT7A |
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Entrez Gene | 7476 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 7A |
Other Description | protein Wnt-7a|proto-oncogene Wnt7a protein |
Swissprots | Q9Y560 Q96H90 O00755 |
Accessions | CAI38648 EAW64173 EAW64174 O00755 BC008811 AAH08811 D83175 BAA82509 DQ893023 ABM83949 DQ896267 ABM87266 U53476 AAC51319 XM_011534090 XP_011532392 XM_011534091 XP_011532393 NM_004625 NP_004616 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain. |
Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |
Wnt-7a CRISPR/Cas9 KO Plasmid (h) - sc-401188 from Santa Cruz Biotechnology
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Wnt-7a HDR Plasmid (h) - sc-401188-HDR from Santa Cruz Biotechnology
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Wnt-7a Double Nickase Plasmid (h) - sc-401188-NIC from Santa Cruz Biotechnology
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Wnt-7a Double Nickase Plasmid (h2) - sc-401188-NIC-2 from Santa Cruz Biotechnology
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Wnt-7a CRISPR Activation Plasmid (h) - sc-401188-ACT from Santa Cruz Biotechnology
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Wnt-7a CRISPR Activation Plasmid (h2) - sc-401188-ACT-2 from Santa Cruz Biotechnology
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Wnt-7a Lentiviral Activation Particles (h) - sc-401188-LAC from Santa Cruz Biotechnology
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Wnt-7a Lentiviral Activation Particles (h2) - sc-401188-LAC-2 from Santa Cruz Biotechnology
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Wnt-7a siRNA (h) - sc-41114 from Santa Cruz Biotechnology
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Wnt-7a shRNA Plasmid (h) - sc-41114-SH from Santa Cruz Biotechnology
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Wnt-7a shRNA (h) Lentiviral Particles - sc-41114-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU064001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22923 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22923 from Sigma-Aldrich
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WNT7A siRNA (Human) - CRH5115 from Cohesion Biosciences
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WNT7A - MBS8224825 from MyBioSource
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Wnt-7a CRISPR/Cas9 KO Plasmid (h2) - sc-401188-KO-2 from Santa Cruz Biotechnology
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Wnt-7a HDR Plasmid (h2) - sc-401188-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human WNT7A (NM_004625.3) - SHH447352 from Creative biogene
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shRNA set against Human WNT7A(NM_004625.3) - SHL136260 from Creative biogene
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Human WNT7A siRNA - orb265617 from Biorbyt
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WNT7A shRNA Plasmid (Human) - CHH5115 from Cohesion Biosciences
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WNT7A miRNA 3'UTR clone - MiUTR1H-11284 from Creative biogene
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