Gene Symbol | TMC8 |
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Entrez Gene | 147138 |
Alt Symbol | EV2, EVER2, EVIN2 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane channel-like 8 |
Other Description | epidermodysplasia verruciformis 2|epidermodysplasia verruciformis protein 2|transmembrane channel-like protein 8 |
Swissprots | Q2YDC0 Q8N358 Q8IWU7 Q8IU68 Q8NF04 |
Accessions | EAW89494 EAW89495 EAW89496 EAW89497 Q8IU68 AK090478 BAC03459 AK097987 AK125672 AK128327 BAG54660 AK303499 BAG64532 AK310623 AL834508 AY057380 AAL25837 AY099358 AAM44454 AY099359 AAM44455 AY236500 AAP69878 BC028076 BC110296 AAI10297 BC141865 AAI41866 DC407759 XM_011524402 XP_011522704 XM_011524403 XP_011522705 XM_011524404 XP_011522706 XM_011524405 XP_011522707 XM_011524406 XP_011522708 XM_011524407 XP_011522709 XM_011524408 XP_011522710 XM_011524409 XP_011522711 XM_011524410 XP_011522712 XM_011524411 XP_011522713 XR_934395 XR_934397 XR_934398 XR_934400 NM_152468 NP_689681 |
Function | Probable ion channel. {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12426567}; Multi-pass membrane protein {ECO:0000269|PubMed:12426567}. |
Tissue Specificity | Expressed in placenta, prostate and testis. {ECO:0000269|PubMed:12906855}. |
TMC8 CRISPR/Cas9 KO Plasmid (h) - sc-406378 from Santa Cruz Biotechnology
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TMC8 HDR Plasmid (h) - sc-406378-HDR from Santa Cruz Biotechnology
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TMC8 Double Nickase Plasmid (h) - sc-406378-NIC from Santa Cruz Biotechnology
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TMC8 Double Nickase Plasmid (h2) - sc-406378-NIC-2 from Santa Cruz Biotechnology
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TMC8 CRISPR Activation Plasmid (h) - sc-406378-ACT from Santa Cruz Biotechnology
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TMC8 CRISPR Activation Plasmid (h2) - sc-406378-ACT-2 from Santa Cruz Biotechnology
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TMC8 Lentiviral Activation Particles (h) - sc-406378-LAC from Santa Cruz Biotechnology
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TMC8 Lentiviral Activation Particles (h2) - sc-406378-LAC-2 from Santa Cruz Biotechnology
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TMC8 siRNA (h) - sc-94147 from Santa Cruz Biotechnology
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TMC8 shRNA Plasmid (h) - sc-94147-SH from Santa Cruz Biotechnology
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TMC8 shRNA (h) Lentiviral Particles - sc-94147-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU151511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21439 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21439 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03275 from Sigma-Aldrich
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TMC8 siRNA (Human) - CRJ5510 from Cohesion Biosciences
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TMC8 - MBS8239001 from MyBioSource
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TMC8 HDR Plasmid (h2) - sc-406378-HDR-2 from Santa Cruz Biotechnology
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TMC8 CRISPR/Cas9 KO Plasmid (h2) - sc-406378-KO-2 from Santa Cruz Biotechnology
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shRNA set against Human TMC8 (NM_152468.4) - SHH428416 from Creative biogene
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Human TMC8 siRNA - orb276011 from Biorbyt
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TMC8 shRNA Plasmid (Human) - CHJ5510 from Cohesion Biosciences
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TMC8 miRNA 3'UTR clone - MiUTR3H-07990 from Creative biogene
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