Gene Symbol | DPYSL2 |
---|---|
Entrez Gene | 1808 |
Alt Symbol | CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 |
Species | Human |
Gene Type | protein-coding |
Description | dihydropyrimidinase-like 2 |
Other Description | collapsin response mediator protein hCRMP-2|dihydropyrimidinase-related protein 2|unc-33-like phosphoprotein 2 |
Swissprots | Q16555 B4DR31 A8K5H2 D3DSS7 O00424 |
Accessions | BAA86991 CAR95650 CAT03389 EAW63573 EAW63574 Q16555 AB209195 BAD92432 AB370194 BAF94338 AB370195 BAF94339 AK092377 BAC03872 AK223557 BAD97277 AK291287 BAF83976 AK299077 BAG61143 BC056408 AAH56408 BC067109 AAH67109 BP222303 BX461557 BX463316 BX647115 D78013 BAA11191 DA649686 DC333865 DC344356 U17279 AAA93202 X91250 NM_001197293 NP_001184222 NM_001244604 NP_001231533 NM_001386 NP_001377 |
Function | Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. {ECO:0000269|PubMed:11477421, ECO:0000269|PubMed:15466863, ECO:0000269|PubMed:20801876}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:20801876}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20801876}. Membrane {ECO:0000269|PubMed:20801876}. Note=Tightly but non-covalently associated with membranes. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Axon guidance |
CRMP2 peptide - ab196858 from Abcam
|
||||||||||
Human CRMP2 full length protein - ab114269 from Abcam
|
||||||||||
Human CRMP2 peptide - ab99478 from Abcam
|
||||||||||
Human CRMP2 protein fragment - ab114270 from Abcam
|
||||||||||
DPYSL2 / CRMP2 Antibody Blocking Peptide - LS-E18648 from LifeSpan Bioscience
|
||||||||||
DRP2 Antibody Blocking Peptide - LS-E23535 from LifeSpan Bioscience
|
||||||||||
Recombinant Human CRMP2 Protein - H00001808-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human CRMP2 Protein - H00001808-P01 from Novus Biologicals
|
||||||||||
DRP-2-Monoclonal-Antibody-Blocking-Peptide - BP1131a from Abgent, a WuXi AppTec company
|
||||||||||
DPYSL2-Antibody-Center-Blocking-peptide - BP13939c from Abgent, a WuXi AppTec company
|
||||||||||
Human DPYSL2 protein - orb246149 from Biorbyt
|
||||||||||
DPYSL2 Blocking Peptide - 33R-6719 from Fitzgerald
|
||||||||||
DPYSL2 / CRMP2 - H00001808-P01-10 from Acris Antibodies
|
||||||||||
DPYSL2 / CRMP2 - H00001808-P01-25 from Acris Antibodies
|
||||||||||
DPYSL2 / CRMP2 - H00001808-Q01-10 from Acris Antibodies
|
||||||||||
DPYSL2 / CRMP2 - H00001808-Q01-25 from Acris Antibodies
|
||||||||||
DPYSL2 fusion protein - ag5985 from Proteintech Group
|
||||||||||
DPYSL2 fusion protein - Ag5987 from Proteintech Group
|
||||||||||
Recombinant Human DPYSL2, GST-tagged - DPYSL2-101H from Creative Biomart
|
||||||||||
Recombinant Human DPYSL2, GST-tagged - DPYSL2-102H from Creative Biomart
|
||||||||||
CRMP2 (pS522) Blocking Peptide - CBP3902 from Cohesion Biosciences
|
||||||||||
DRP-2 (P510) Peptide - BS3005P from Bioworld Technology
|
||||||||||
CRMP-2 peptide - pep0115 from Covalab
|
||||||||||
Recombinant Human Dihydropyrimidinase-related protein 2(DPYSL2) - CSB-EP614975HU CSB-BP614975HU CSB-MP614975HU from Cusabio
|
||||||||||
Recombinant Human Dihydropyrimidinase-related protein 2(DPYSL2) - CSB-YP614975HU from Cusabio
|