Gene Symbol | FGF3 |
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Entrez Gene | 2248 |
Alt Symbol | HBGF-3, INT2 |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 3 |
Other Description | FGF-3|INT-2 proto-oncogene protein|V-INT2 murine mammary tumor virus integration site oncogene homolog|fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)|heparin-binding growth factor 3|murine mammary tumor virus integration site 2, mouse|oncogene INT2|proto-oncogene Int-2 |
Swissprots | P11487 Q0VG69 |
Accessions | CAA32615 EAW74753 EAW74754 P11487 BC113739 AAI13740 NM_005247 NP_005238 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development. {ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted {ECO:0000305}. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF-3 CRISPR/Cas9 KO Plasmid (h) - sc-404553 from Santa Cruz Biotechnology
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FGF-3 HDR Plasmid (h) - sc-404553-HDR from Santa Cruz Biotechnology
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FGF-3 Double Nickase Plasmid (h) - sc-404553-NIC from Santa Cruz Biotechnology
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FGF-3 Double Nickase Plasmid (h2) - sc-404553-NIC-2 from Santa Cruz Biotechnology
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FGF-3 CRISPR Activation Plasmid (h) - sc-404553-ACT from Santa Cruz Biotechnology
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FGF-3 CRISPR Activation Plasmid (h2) - sc-404553-ACT-2 from Santa Cruz Biotechnology
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FGF-3 Lentiviral Activation Particles (h) - sc-404553-LAC from Santa Cruz Biotechnology
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FGF-3 Lentiviral Activation Particles (h2) - sc-404553-LAC-2 from Santa Cruz Biotechnology
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FGF-3 siRNA (h) - sc-39448 from Santa Cruz Biotechnology
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FGF-3 shRNA Plasmid (h) - sc-39448-SH from Santa Cruz Biotechnology
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FGF-3 shRNA (h) Lentiviral Particles - sc-39448-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN8660 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8660 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02729 from Sigma-Aldrich
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FGF3 siRNA (Human) - CRH1568 from Cohesion Biosciences
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FGF3 - MBS8228424 from MyBioSource
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shRNA set against Human Fgf3 (NM_005247.2) - SHH294541 from Creative biogene
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shRNA set against Human FGF3(NM_005247.2) - SHH057685 from Creative biogene
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Human FGF3 siRNA - orb262070 from Biorbyt
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FGF3 shRNA Plasmid (Human) - CHH1568 from Cohesion Biosciences
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FGF3 miRNA 3'UTR clone - MiUTR1H-03632 from Creative biogene
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