Gene Symbol | IQGAP2 |
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Entrez Gene | 10788 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | IQ motif containing GTPase activating protein 2 |
Other Description | ras GTPase-activating-like protein IQGAP2 |
Swissprots | B7Z8A4 A8K4V1 Q13576 J3KR91 |
Accessions | EAW95775 EAW95776 EAW95777 Q13576 AB208856 BAD92093 AK291066 BAF83755 AK302510 BAH13732 AK302599 BAH13758 AK302981 BAH13867 AK303054 BAH13890 AK307555 AK307626 AK311619 AY351902 AAQ81291 BI481276 BQ002800 DB071610 DB075371 U51903 AAB37765 XM_005248410 XP_005248467 XM_005248414 XP_005248471 XM_011543107 XP_011541409 XM_011543108 XP_011541410 NM_001285460 NP_001272389 NM_001285461 NP_001272390 NM_001285462 NP_001272391 NM_006633 NP_006624 |
Function | Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. |
Tissue Specificity | Isoform 2 expression is enhanced in testis. |
Top Pathways | Regulation of actin cytoskeleton |
IQGAP2 CRISPR/Cas9 KO Plasmid (h) - sc-402124 from Santa Cruz Biotechnology
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IQGAP2 HDR Plasmid (h) - sc-402124-HDR from Santa Cruz Biotechnology
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IQGAP2 Double Nickase Plasmid (h) - sc-402124-NIC from Santa Cruz Biotechnology
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IQGAP2 Double Nickase Plasmid (h2) - sc-402124-NIC-2 from Santa Cruz Biotechnology
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IQGAP2 CRISPR Activation Plasmid (h) - sc-402124-ACT from Santa Cruz Biotechnology
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IQGAP2 CRISPR Activation Plasmid (h2) - sc-402124-ACT-2 from Santa Cruz Biotechnology
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IQGAP2 Lentiviral Activation Particles (h) - sc-402124-LAC from Santa Cruz Biotechnology
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IQGAP2 Lentiviral Activation Particles (h2) - sc-402124-LAC-2 from Santa Cruz Biotechnology
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IQGAP2 siRNA (h) - sc-35702 from Santa Cruz Biotechnology
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IQGAP2 shRNA Plasmid (h) - sc-35702-SH from Santa Cruz Biotechnology
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IQGAP2 shRNA (h) Lentiviral Particles - sc-35702-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU007421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10754 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10754 from Sigma-Aldrich
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IQGAP2 siRNA (Human) - CRH7352 from Cohesion Biosciences
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IQGAP2 RNAi - H00010788-R01 from Novus Biologicals
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IQGAP2 - MBS8228064 from MyBioSource
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shRNA set against Human IQGAP2 (NM_006633.2) - SHH320421 from Creative biogene
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shRNA set against Human IQGAP2(NM_006633.2) - SHL173250 from Creative biogene
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IQGAP2 shRNA Plasmid (Human) - CHH7352 from Cohesion Biosciences
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IQGAP2 miRNA 3'UTR clone - MiUTR1H-04983 from Creative biogene
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