Gene Symbol | MVK |
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Entrez Gene | 4598 |
Alt Symbol | LRBP, MK, MVLK, POROK3 |
Species | Human |
Gene Type | protein-coding |
Description | mevalonate kinase |
Other Description | LH receptor mRNA-binding protein|mevalonate kinase 1 |
Swissprots | Q03426 |
Accessions | AAF82407 ACS13750 ACS13751 EAW97870 EAW97871 EAW97872 EAW97873 Q03426 AB209722 BAD92959 AF217536 AAF82406 AK023087 AK293130 BAH11458 AK295338 BAH12037 AK315678 BAG38043 BC016140 AAH16140 DC421549 DQ891089 ABM82015 DQ894271 ABM85197 M88468 AAB59362 R51202 XM_011538372 XP_011536674 NM_000431 NP_000422 NM_001114185 NP_001107657 NM_001301182 NP_001288111 |
Function | May be a regulatory site in cholesterol biosynthetic pathway. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14730012}. |
Top Pathways | Terpenoid backbone biosynthesis, Peroxisome |
MVK CRISPR/Cas9 KO Plasmid (h) - sc-406617 from Santa Cruz Biotechnology
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MVK HDR Plasmid (h) - sc-406617-HDR from Santa Cruz Biotechnology
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MVK Double Nickase Plasmid (h) - sc-406617-NIC from Santa Cruz Biotechnology
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MVK Double Nickase Plasmid (h2) - sc-406617-NIC-2 from Santa Cruz Biotechnology
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MVK CRISPR Activation Plasmid (h) - sc-406617-ACT from Santa Cruz Biotechnology
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MVK CRISPR Activation Plasmid (h2) - sc-406617-ACT-2 from Santa Cruz Biotechnology
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MVK Lentiviral Activation Particles (h) - sc-406617-LAC from Santa Cruz Biotechnology
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MVK Lentiviral Activation Particles (h2) - sc-406617-LAC-2 from Santa Cruz Biotechnology
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MVK siRNA (h) - sc-106266 from Santa Cruz Biotechnology
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MVK shRNA Plasmid (h) - sc-106266-SH from Santa Cruz Biotechnology
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MVK shRNA (h) Lentiviral Particles - sc-106266-V from Santa Cruz Biotechnology
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MVK RNAi - H00004598-R02 from Novus Biologicals
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MISSION® esiRNA - EHU058101 from Sigma-Aldrich
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MISSION® siRNA - SIHK1338 from Sigma-Aldrich
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MISSION® siRNA - SIHK1339 from Sigma-Aldrich
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MISSION® siRNA - SIHK1337 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14777 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14777 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05769 from Sigma-Aldrich
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MVK siRNA (Human) - CRH3029 from Cohesion Biosciences
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shRNA set against Human MVK (NM_000431.2) - SHH347256 from Creative biogene
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shRNA set against Human MVK(NM_000431.2) - SHH209423 from Creative biogene
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MVK shRNA Plasmid (Human) - CHH3029 from Cohesion Biosciences
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MVK miRNA 3'UTR clone - MiUTR1H-06539 from Creative biogene
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MVK miRNA 3'UTR clone - MiUTR3H-02479 from Creative biogene
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