| Gene Symbol |
GDPD2
|
| Entrez Gene |
54857
|
| Alt Symbol |
GDE3, OBDPF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycerophosphodiester phosphodiesterase domain containing 2
|
| Other Description |
glycerophosphodiester phosphodiesterase 3|glycerophosphodiester phosphodiesterase domain-containing protein 2|glycerophosphoinositol inositolphosphodiesterase GDPD2|osteoblast differentiation promoting factor
|
| Swissprots |
B4DVC9 Q9HCC8 B4DRH4 Q9NXJ6
|
| Accessions |
EAX05339 EAX05340 Q9HCC8 AB048363 BAB13350 AI277430 AK000214 BAA91014 AK097293 BAG53448 AK299255 BAG61286 AK301025 BAG62641 AK307778 AK310090 AK316035 BAH14406 AY358986 AAQ89345 BC032009 AAH32009 DA934769 GQ129325 ACT64459 GQ129326 ACT64460 XM_011530977 XP_011529279 NM_001171191 NP_001164662 NM_001171192 NP_001164663 NM_001171193 NP_001164664 NM_017711 NP_060181
|
| Function |
Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with the actin cytoskeleton. {ECO:0000250}.
|
![Western Blot: GDPD2 Overexpression Lysate (Adult Normal) [NBL1-11033] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDPD2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9329_GDPD2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11033-img0002.jpg)