Gene Symbol |
ESAM
|
Entrez Gene |
90952
|
Alt Symbol |
W117m
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
endothelial cell adhesion molecule
|
Other Description |
2310008D05Rik|HUEL (C4orf1)-interacting protein|LP4791 protein|endothelial cell-selective adhesion molecule
|
Swissprots |
Q96T50 Q96AP7 B4DVN8
|
Accessions |
CAI72094 EAW67598 Q96AP7 AF277292 AAF97236 AF361746 AAK51065 AK075396 BAC11594 AK091023 AK092429 AK301160 BAG62750 AK314710 AY189281 AAO86725 AY358382 AAQ88748 BC016868 AAH16868 DA257581 DQ891768 ABM82694 DQ894952 ABM85878 XM_005271720 XP_005271777 XM_011543060 XP_011541362 XR_246456 NM_138961 NP_620411
|
Function |
Can mediate aggregation most likely through a homophilic molecular interaction. {ECO:0000250}.
|
Subcellular Location |
Cell junction, adherens junction {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in endothelial cells. {ECO:0000269|PubMed:11279107}.
|
Top Pathways |
Leukocyte transendothelial migration, Cell adhesion molecules (CAMs)
|