Gene Symbol | ESAM |
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Entrez Gene | 90952 |
Alt Symbol | W117m |
Species | Human |
Gene Type | protein-coding |
Description | endothelial cell adhesion molecule |
Other Description | 2310008D05Rik|HUEL (C4orf1)-interacting protein|LP4791 protein|endothelial cell-selective adhesion molecule |
Swissprots | Q96T50 Q96AP7 B4DVN8 |
Accessions | CAI72094 EAW67598 Q96AP7 AF277292 AAF97236 AF361746 AAK51065 AK075396 BAC11594 AK091023 AK092429 AK301160 BAG62750 AK314710 AY189281 AAO86725 AY358382 AAQ88748 BC016868 AAH16868 DA257581 DQ891768 ABM82694 DQ894952 ABM85878 XM_005271720 XP_005271777 XM_011543060 XP_011541362 XR_246456 NM_138961 NP_620411 |
Function | Can mediate aggregation most likely through a homophilic molecular interaction. {ECO:0000250}. |
Subcellular Location | Cell junction, adherens junction {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Highly expressed in endothelial cells. {ECO:0000269|PubMed:11279107}. |
Top Pathways | Leukocyte transendothelial migration, Cell adhesion molecules (CAMs) |
ESAM CRISPR/Cas9 KO Plasmid (h) - sc-413872 from Santa Cruz Biotechnology
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ESAM HDR Plasmid (h) - sc-413872-HDR from Santa Cruz Biotechnology
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ESAM Double Nickase Plasmid (h) - sc-413872-NIC from Santa Cruz Biotechnology
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ESAM Double Nickase Plasmid (h2) - sc-413872-NIC-2 from Santa Cruz Biotechnology
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ESAM CRISPR Activation Plasmid (h) - sc-413872-ACT from Santa Cruz Biotechnology
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ESAM CRISPR Activation Plasmid (h2) - sc-413872-ACT-2 from Santa Cruz Biotechnology
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ESAM Lentiviral Activation Particles (h) - sc-413872-LAC from Santa Cruz Biotechnology
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ESAM Lentiviral Activation Particles (h2) - sc-413872-LAC-2 from Santa Cruz Biotechnology
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ESAM siRNA (h) - sc-77286 from Santa Cruz Biotechnology
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ESAM shRNA Plasmid (h) - sc-77286-SH from Santa Cruz Biotechnology
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ESAM shRNA (h) Lentiviral Particles - sc-77286-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU016391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7981 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03932 from Sigma-Aldrich
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ESAM siRNA (Human) - CRJ3998 from Cohesion Biosciences
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ESAM - MBS8228277 from MyBioSource
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shRNA set against Human ESAM (NM_138961.2) - SHH287293 from Creative biogene
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shRNA set against Human ESAM(NM_138961.2) - SHG210295 from Creative biogene
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Human ESAM siRNA - orb274499 from Biorbyt
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ESAM shRNA Plasmid (Human) - CHJ3998 from Cohesion Biosciences
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ESAM miRNA 3'UTR clone - MiUTR3H-13202 from Creative biogene
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