| Gene Symbol | C8B |
|---|---|
| Entrez Gene | 732 |
| Alt Symbol | C82 |
| Species | Human |
| Gene Type | protein-coding |
| Description | complement component 8, beta polypeptide |
| Other Description | complement component 8 subunit beta|complement component C8 beta chain |
| Swissprots | A1L4K7 P07358 |
| Accessions | EAX06641 EAX06642 EAX06643 P07358 AK292740 BAF85429 AK298425 BAH12786 AK298444 BAH12791 AK313382 BAG36180 AK316209 BAH14580 BC020701 AAH20701 BC130575 AAI30576 CD364465 HQ258464 ADR83218 M16973 AAA51862 X04393 CAA27981 NM_000066 NP_000057 NM_001278543 NP_001265472 NM_001278544 NP_001265473 |
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. |
| Subcellular Location | Secreted. |
| Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis |