Gene Symbol | C8B |
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Entrez Gene | 732 |
Alt Symbol | C82 |
Species | Human |
Gene Type | protein-coding |
Description | complement component 8, beta polypeptide |
Other Description | complement component 8 subunit beta|complement component C8 beta chain |
Swissprots | A1L4K7 P07358 |
Accessions | EAX06641 EAX06642 EAX06643 P07358 AK292740 BAF85429 AK298425 BAH12786 AK298444 BAH12791 AK313382 BAG36180 AK316209 BAH14580 BC020701 AAH20701 BC130575 AAI30576 CD364465 HQ258464 ADR83218 M16973 AAA51862 X04393 CAA27981 NM_000066 NP_000057 NM_001278543 NP_001265472 NM_001278544 NP_001265473 |
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis |
C8β siRNA (h) - sc-88726 from Santa Cruz Biotechnology
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C8β shRNA Plasmid (h) - sc-88726-SH from Santa Cruz Biotechnology
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C8β shRNA (h) Lentiviral Particles - sc-88726-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5124 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5124 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01232 from Sigma-Aldrich
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C8B siRNA (Human) - CRH0509 from Cohesion Biosciences
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C8B - MBS8241185 from MyBioSource
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shRNA set against Human C8b (NM_000066.2) - SHH252593 from Creative biogene
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shRNA set against Human C8B(NM_000066.2) - SHG128773 from Creative biogene
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C8B shRNA Plasmid (Human) - CHH0509 from Cohesion Biosciences
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C8B miRNA 3'UTR clone - MiUTR1H-01494 from Creative biogene
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