| Gene Symbol | ADRB3 |
|---|---|
| Entrez Gene | 155 |
| Alt Symbol | BETA3AR |
| Species | Human |
| Gene Type | protein-coding |
| Description | adrenoceptor beta 3 |
| Other Description | adrenergic, beta-3-, receptor|beta-3 adrenergic receptor|beta-3 adrenoceptor|beta-3 adrenoreceptor |
| Swissprots | P13945 Q4JFT4 |
| Accessions | AAA35550 AAY88743 CAA50142 CAA50143 CAA51383 EAW63343 EAW63344 P13945 AK293033 BAF85722 AK309919 AK313857 BAG36585 AY487247 AAR37414 BC075017 AAH75017 BQ024407 DA904248 FJ170286 ACL14174 FJ170287 ACL14175 S53291 AAB24837 X70811 CAA50141 NM_000025 NP_000016 |
| Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed mainly in adipose tissues. |
| Top Pathways | Calcium signaling pathway, Endocytosis, Salivary secretion, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction |