PI4KB

Gene Symbol	PI4KB
Entrez Gene	5298
Alt Symbol	NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIIIBETA, PIK4CB
Species	Human
Gene Type	protein-coding
Description	phosphatidylinositol 4-kinase, catalytic, beta
Other Description	PtdIns 4-kinase beta|phosphatidylinositol 4-kinase beta|phosphatidylinositol 4-kinase, wortmannin-sensitive|type III phosphatidylinositol 4-kinase beta
Swissprots	Q5VWB9 P78405 Q9BWR6 B4DGI2 Q9UBF8 Q5VWC0 O15096 Q5VWC1
Accessions	CAC69371 EAW53449 EAW53450 Q9UBF8 AB005910 BAA21661 AJ011121 CAA09495 AK054691 AK294606 BAG57793 AK311292 AL832188 BC000029 AAH00029 BC040300 AAH40300 DC350175 DC365634 U81802 AAC51156 XM_005245264 XP_005245321 XM_011509634 XP_011507936 XM_011509635 XP_011507937 XM_011509636 XP_011507938 XM_011509637 XP_011507939 XM_011509638 XP_011507940 NM_001198773 NP_001185702 NM_001198774 NP_001185703 NM_001198775 NP_001185704 NM_002651 NP_002642
Function	Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity). {ECO:0000250}.
Subcellular Location	Endomembrane system. Mitochondrion outer membrane; Peripheral membrane protein. Rough endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus. Cytoplasm, perinuclear region. Note=Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
Tissue Specificity	Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver. {ECO:0000269|PubMed:9020160, ECO:0000269|PubMed:9405935, ECO:0000269|PubMed:9405938}.
Top Pathways	Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PI4 kinase beta full length protein - ab105199 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Human PI4 kinase beta full length protein - ab152609 from Abcam Category Protein Source Wheat germ Species Human

Human PI4 kinase beta protein fragment - ab152610 from Abcam Category Protein Source Wheat germ Species Human

PIK4CB / PI4KB Antibody Blocking Peptide - LS-E20464 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PIK4CB / PI4KB Antibody Blocking Peptide - LS-E20465 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PIK4CB / PI4KB Antibody Blocking Peptide - LS-E8568 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PI4KB/PI4KIII beta Protein - H00005298-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PI4KB/PI4KIII beta Protein - H00005298-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PI4KB/PI4KIII beta Peptide - P3014 from Novus Biologicals Category Peptide Species Human

PIK4CB-Antibody-Center-Blocking-Peptide - BP6948c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PIK4CB-Antibody-N-term-Blocking-Peptide - BP6948a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PI4KCB-Antibody-N-term-Blocking-Peptide - BP8030a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PI4KB Blocking Peptide - 33R-3795 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PI4KB Blocking Peptide - 33R-5051 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PI4KB - H00005298-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PI4KB - H00005298-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PI4KB - H00005298-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PI4KB - H00005298-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PI4KB fusion protein - ag7372 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PI4KB fusion protein - Ag3989 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PI4KB fusion protein - Ag7490 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human PI4KB - PI4KB-30364TH from Creative Biomart Category Protein Source Baculovirus infected sf9 cells

Recombinant Human PI4KB, GST-tagged - PI4KB-1702H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PI4KB, GST-tagged - PI4KB-1077H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant Human Phosphatidylinositol 4-kinase beta(PI4KB) ,partial - CSB-YP883360HU CSB-EP883360HU CSB-BP883360HU CSB-MP883360HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Search more