Gene Symbol | CD300LF |
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Entrez Gene | 146722 |
Alt Symbol | CD300f, CLM-1, CLM1, IREM-1, IREM1, IgSF13, LMIR3, NKIR |
Species | Human |
Gene Type | protein-coding |
Description | CD300 molecule-like family member f |
Other Description | CD300 antigen-like family member F|CD300 molecule like family member f|CMRF35-like molecule 1|NK inhibitory receptor|immune receptor expressed on myeloid cells 1|immunoglobin superfamily member 13|immunoglobulin superfamily member 13|inhibitory receptor IREM1 |
Swissprots | Q6UX24 Q7Z7I4 C9JDN3 Q8N6D0 Q8TDQ1 B2RCL2 Q7Z7I5 Q7Z6A6 Q3Y6P0 Q8NAF5 |
Accessions | CBX47386 EAW89184 EAW89185 EAW89186 EAW89187 Q8TDQ1 AF251706 AAM19099 AF375480 AAP42152 AF375481 AAP42153 AK092757 BAC03966 AK298752 BAG60894 AK315165 BAG37609 AY303545 AAP57942 AY358545 AAQ88909 BC028199 AAH28199 BI911496 BM147210 BM680508 BM922663 BM923728 BP226373 DA673169 DQ153249 AAZ81566 XM_011524369 XP_011522671 XM_011524370 XP_011522672 XM_011524371 XP_011522673 XM_011524372 XP_011522674 XM_011524373 XP_011522675 XM_011524374 XP_011522676 XM_011524375 XP_011522677 XM_011524376 XP_011522678 XM_011524377 XP_011522679 XM_011524378 XP_011522680 XM_011524379 XP_011522681 NM_001289082 NP_001276011 NM_001289083 NP_001276012 NM_001289084 NP_001276013 NM_001289085 NP_001276014 NM_001289086 NP_001276015 NM_001289087 NP_001276016 NM_139018 NP_620587 NR_110298 |
Function | Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. {ECO:0000269|PubMed:15549731}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells. {ECO:0000269|PubMed:15184070, ECO:0000269|PubMed:15549731}. |
CD300LF CRISPR/Cas9 KO Plasmid (h) - sc-408327 from Santa Cruz Biotechnology
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CD300LF HDR Plasmid (h) - sc-408327-HDR from Santa Cruz Biotechnology
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CD300LF Double Nickase Plasmid (h) - sc-408327-NIC from Santa Cruz Biotechnology
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CD300LF Double Nickase Plasmid (h2) - sc-408327-NIC-2 from Santa Cruz Biotechnology
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CD300LF CRISPR Activation Plasmid (h) - sc-408327-ACT from Santa Cruz Biotechnology
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CD300LF CRISPR Activation Plasmid (h2) - sc-408327-ACT-2 from Santa Cruz Biotechnology
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CD300LF Lentiviral Activation Particles (h) - sc-408327-LAC from Santa Cruz Biotechnology
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CD300LF Lentiviral Activation Particles (h2) - sc-408327-LAC-2 from Santa Cruz Biotechnology
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CD300LF siRNA (h) - sc-94217 from Santa Cruz Biotechnology
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CD300LF shRNA Plasmid (h) - sc-94217-SH from Santa Cruz Biotechnology
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CD300LF shRNA (h) Lentiviral Particles - sc-94217-V from Santa Cruz Biotechnology
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CD300f/LMIR3/CD300LF RNAi - H00146722-R02 from Novus Biologicals
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MISSION® esiRNA - EHU123771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5717 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5717 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07211 from Sigma-Aldrich
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CD300LF siRNA (Human) - CRJ5486 from Cohesion Biosciences
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CD300LF - MBS8223038 from MyBioSource
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shRNA set against Human CD300LF (NM_139018.3) - SHH258937 from Creative biogene
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shRNA set against Human CD300LF(NM_139018.3) - SHG156529 from Creative biogene
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CD300LF shRNA Plasmid (Human) - CHJ5486 from Cohesion Biosciences
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CD300LF miRNA 3'UTR clone - MiUTR1H-01866 from Creative biogene
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