Gene Symbol | POLN |
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Entrez Gene | 353497 |
Alt Symbol | POL4P |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (DNA directed) nu |
Other Description | DNA polymerase N|DNA polymerase POL4P|DNA polymerase nu |
Swissprots | Q6ZNF4 Q4TTW4 A2A336 B4E158 Q7Z5Q5 |
Accessions | AAY43130 EAW82538 EAW82539 Q7Z5Q5 AF044578 AAD02338 AK131239 BAD18421 AK303673 BAG64670 AL122048 AY136549 AAN52116 BC146297 AAI46298 BC156716 AAI56717 BC156871 AAI56872 BX509164 DB098342 HY010559 NM_181808 NP_861524 |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12794064}. |
Tissue Specificity | Highly expressed in testis and heart. Weakly expressed in skeletal muscle. {ECO:0000269|PubMed:12794064}. |
Top Pathways | Fanconi anemia pathway |
DNA pol ν CRISPR/Cas9 KO Plasmid (h) - sc-406518 from Santa Cruz Biotechnology
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DNA pol ν HDR Plasmid (h) - sc-406518-HDR from Santa Cruz Biotechnology
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DNA pol ν Double Nickase Plasmid (h) - sc-406518-NIC from Santa Cruz Biotechnology
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DNA pol ν Double Nickase Plasmid (h2) - sc-406518-NIC-2 from Santa Cruz Biotechnology
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DNA pol ν CRISPR Activation Plasmid (h) - sc-406518-ACT from Santa Cruz Biotechnology
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DNA pol ν CRISPR Activation Plasmid (h2) - sc-406518-ACT-2 from Santa Cruz Biotechnology
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DNA pol ν Lentiviral Activation Particles (h) - sc-406518-LAC from Santa Cruz Biotechnology
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DNA pol ν Lentiviral Activation Particles (h2) - sc-406518-LAC-2 from Santa Cruz Biotechnology
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DNA pol ν siRNA (h) - sc-89311 from Santa Cruz Biotechnology
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DNA pol ν shRNA Plasmid (h) - sc-89311-SH from Santa Cruz Biotechnology
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DNA pol ν shRNA (h) Lentiviral Particles - sc-89311-V from Santa Cruz Biotechnology
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POLN RNAi - H00353497-R01 from Novus Biologicals
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MISSION® esiRNA - EHU097191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17104 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17104 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00928 from Sigma-Aldrich
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POLN siRNA (Human) - CRJ7591 from Cohesion Biosciences
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shRNA set against Human POLN (NM_181808.2) - SHH379296 from Creative biogene
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shRNA set against Human POLN(NM_181808.2) - SHR127086 from Creative biogene
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Human POLN siRNA - orb278092 from Biorbyt
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POLN shRNA Plasmid (Human) - CHJ7591 from Cohesion Biosciences
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POLN miRNA 3'UTR clone - MiUTR1H-08068 from Creative biogene
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