Gene Symbol | INPP4B |
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Entrez Gene | 8821 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | inositol polyphosphate-4-phosphatase, type II, 105kDa |
Other Description | inositol polyphosphate 4-phosphatase II; 4-phosphatase II|inositol polyphosphate 4-phosphatase type II|inositol polyphosphate-4-phosphatase, type II, 105kD|type II inositol 3,4-bisphosphate 4-phosphatase|type II inositol-3,4-bisphosphate 4-phosphatase |
Swissprots | Q6IN59 Q5XLE7 Q6PJB4 O15327 Q2TAI2 |
Accessions | EAX05081 O15327 AK298118 BAH12726 AK300891 BAH13368 AK302936 BAH13850 AY753912 AAV28485 BC005273 AAH05273 BC005274 BC017924 AAH17924 BC072447 AAH72447 BC110918 AAI10919 BC133005 AAI33006 BC144255 BP360389 BX649090 U96922 AAB72153 XM_005263322 XP_005263379 XM_005263323 XP_005263380 XM_005263325 XP_005263382 XM_006714400 XP_006714463 XM_006714401 XP_006714464 XM_006714402 XP_006714465 XM_006714403 XP_006714466 XM_006714404 XP_006714467 XM_011532391 XP_011530693 XM_011532392 XP_011530694 XM_011532393 XP_011530695 XM_011532394 XP_011530696 XM_011532395 XP_011530697 XM_011532396 XP_011530698 XR_938790 XR_938791 NM_001101669 NP_001095139 NM_003866 NP_003857 |
Function | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate. |
Tissue Specificity | Widely expressed with highest levels occurring in the skeletal muscle and heart. {ECO:0000269|PubMed:9295334}. |
Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
Type II 4-phosphatase CRISPR/Cas9 KO Plasmid (h) - sc-402205 from Santa Cruz Biotechnology
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Type II 4-phosphatase HDR Plasmid (h) - sc-402205-HDR from Santa Cruz Biotechnology
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Type II 4-phosphatase Double Nickase Plasmid (h) - sc-402205-NIC from Santa Cruz Biotechnology
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Type II 4-phosphatase Double Nickase Plasmid (h2) - sc-402205-NIC-2 from Santa Cruz Biotechnology
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Type II 4-phosphatase CRISPR Activation Plasmid (h) - sc-402205-ACT from Santa Cruz Biotechnology
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Type II 4-phosphatase CRISPR Activation Plasmid (h2) - sc-402205-ACT-2 from Santa Cruz Biotechnology
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Type II 4-phosphatase Lentiviral Activation Particles (h) - sc-402205-LAC from Santa Cruz Biotechnology
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Type II 4-phosphatase Lentiviral Activation Particles (h2) - sc-402205-LAC-2 from Santa Cruz Biotechnology
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Type II 4-phosphatase siRNA (h) - sc-44178 from Santa Cruz Biotechnology
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Type II 4-phosphatase shRNA Plasmid (h) - sc-44178-SH from Santa Cruz Biotechnology
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Type II 4-phosphatase shRNA (h) Lentiviral Particles - sc-44178-V from Santa Cruz Biotechnology
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INPP4B RNAi - H00008821-R01 from Novus Biologicals
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MISSION® esiRNA - EHU099241 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0970 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0266 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0971 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0265 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0267 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1028 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1028 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06534 from Sigma-Aldrich
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INPP4B siRNA (Human) - CRH5819 from Cohesion Biosciences
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INPP4B - MBS8237050 from MyBioSource
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shRNA set against Human INPP4B (NM_003866.2) - SHH319685 from Creative biogene
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shRNA set against Human INPP4B(NM_003866.2) - SHL178028 from Creative biogene
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