Gene Symbol | TBXAS1 |
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Entrez Gene | 6916 |
Alt Symbol | BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS |
Species | Human |
Gene Type | protein-coding |
Description | thromboxane A synthase 1 (platelet) |
Other Description | TXA synthase|cytochrome P450 5A1|cytochrome P450, family 5, subfamily A, polypeptide 1|platelet, cytochrome P450, subfamily V|thromboxane-A synthase |
Swissprots | Q9HD82 Q9HD81 Q9HD79 Q16844 Q9HD78 Q96CN2 B4DJG6 Q9HD77 E7EMU9 Q9HD80 P24557 E7ESB5 Q8IUN1 Q9HD84 Q16843 O14987 E7EP08 Q9GZW4 Q9HD83 |
Accessions | AAC01761 AAD21788 AAF99269 AAF99270 AAF99271 AAF99272 AAF99273 AAF99274 AAF99275 AAF99276 AAF99277 AAF99278 AAF99279 AAP21887 BAA07011 EAW83934 EAW83935 EAW83936 P24557 AK223466 BAD97186 AK296069 BAG58828 AK301049 BAH13397 AK301164 BAG62753 AK303440 BAG64487 AU099213 BC014117 AAH14117 BC041157 AAH41157 BM673654 HQ447293 ADQ31780 M74055 AAA36742 M80646 AAA60617 M80647 AAA60618 S60133 XM_011516544 XP_011514846 NM_001061 NP_001052 NM_001130966 NP_001124438 NM_001166253 NP_001159725 NM_001166254 NP_001159726 NM_030984 NP_112246 NR_029394 |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:8366093}; Multi-pass membrane protein {ECO:0000269|PubMed:8366093}. |
Tissue Specificity | Platelets, lung, kidney, spleen, macrophages and lung fibroblasts. |
Top Pathways | Arachidonic acid metabolism |
TXA synthase CRISPR/Cas9 KO Plasmid (h) - sc-418609 from Santa Cruz Biotechnology
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TXA synthase HDR Plasmid (h) - sc-418609-HDR from Santa Cruz Biotechnology
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TXA synthase Double Nickase Plasmid (h) - sc-418609-NIC from Santa Cruz Biotechnology
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TXA synthase Double Nickase Plasmid (h2) - sc-418609-NIC-2 from Santa Cruz Biotechnology
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TXA synthase CRISPR Activation Plasmid (h) - sc-418609-ACT from Santa Cruz Biotechnology
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TXA synthase CRISPR Activation Plasmid (h2) - sc-418609-ACT-2 from Santa Cruz Biotechnology
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TXA synthase Lentiviral Activation Particles (h) - sc-418609-LAC from Santa Cruz Biotechnology
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TXA synthase Lentiviral Activation Particles (h2) - sc-418609-LAC-2 from Santa Cruz Biotechnology
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TXA synthase siRNA (h) - sc-62451 from Santa Cruz Biotechnology
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TXA synthase shRNA Plasmid (h) - sc-62451-SH from Santa Cruz Biotechnology
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TXA synthase shRNA (h) Lentiviral Particles - sc-62451-V from Santa Cruz Biotechnology
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Thromboxane synthase RNAi - H00006916-R02 from Novus Biologicals
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MISSION® esiRNA - EHU060341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1893 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1893 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00592 from Sigma-Aldrich
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TBXAS1 siRNA (Human) - CRH4740 from Cohesion Biosciences
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Thromboxane synthase RNAi - H00006916-R01 from Novus Biologicals
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TBXAS1 - MBS8228183 from MyBioSource
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shRNA set against Human TBXAS1 (NM_001061.4) - SHH424500 from Creative biogene
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Human TBXAS1 siRNA - orb265242 from Biorbyt
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TBXAS1 shRNA Plasmid (Human) - CHH4740 from Cohesion Biosciences
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TBXAS1 miRNA 3'UTR clone - MiUTR3H-02482 from Creative biogene
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TBXAS1 miRNA 3'UTR clone - MiUTR3H-02483 from Creative biogene
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TBXAS1 miRNA 3'UTR clone - MiUTR3H-02484 from Creative biogene
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