| Gene Symbol |
Faah
|
| Entrez Gene |
14073
|
| Alt Symbol |
AW412498
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
fatty acid amide hydrolase
|
| Other Description |
amide hydrolase|anandamide amidohydrolase 1|fatty acid amide hydrolase protein|fatty-acid amide hydrolase 1|oleamide hydrolase 1
|
| Swissprots |
O08914 Q9DBF5 Q922S0
|
| Accessions |
AAD11788 AAM76081 AAM77217 EDL30625 EDL30626 EDL30627 O08914 AK004985 AK032079 AK079598 BAC37695 AK080603 AK138481 BAE23677 BC006863 AAH06863 BC052321 AAH52321 BY657662 U82536 AAB58506 NM_010173 NP_034303
|
| Function |
Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=Seems to be associated with the endoplasmic reticulum and/or Golgi apparatus.
|
| Top Pathways |
Retrograde endocannabinoid signaling
|